Systems and methods of stimulation and activation of fluids for use with instillation therapy

Patent metadata

Field	Value
Publication number	US-2017239096-A1
Application number	US-201715456886-A
Country	US
Kind code	A1
Filing date	Mar 13, 2017
Priority date	May 26, 2011
Publication date	Aug 24, 2017
Grant date	—

Abstract

Systems and methods of stimulating or activating fluids for use in wound treatment systems.

First claim

We claim:

1 . A wound treatment system comprising:
a wound dressing; a fluid storage device configured to deliver a fluid to the wound dressing, wherein the fluid comprises molecules with a protective coating; and an energy source configured to direct ultrasonic energy to the fluid and to degrade the protective coating and to activate a therapeutic property of the fluid.

2 . (canceled)

3 . (canceled)

4 . The wound treatment system of claim 1 , wherein the energy source is configured to activate a component of the fluid that degrades the protective coating.

5 . The wound treatment system of claim 1 , wherein the protective coating comprises a bioabsorbable glass.

6 . The wound treatment system of claim 1 , wherein the protective coating comprises a ceramic.

7 . (canceled)

8 . (canceled)

9 . (canceled)

10 . (canceled)

11 . (canceled)

12 . The wound treatment system of claim 1 , wherein the energy source is configured to direct energy to the fluid proximal to the wound dressing.

13 . The wound treatment system of claim 1 , further comprising a conduit in fluid communication with the fluid storage device and the wound dressing.

14 . The wound treatment system of claim 13 , wherein the energy source is configured to direct energy to the fluid in the conduit.

15 . The wound treatment system of claim 1 , wherein the therapeutic property includes an anti-biotic property.

16 . The wound treatment system of claim 1 , wherein the therapeutic property includes an analgesic property.

17 . The wound treatment system of claim 1 , wherein the therapeutic property aids with debridement of tissue.

18 . The wound treatment system of claim 1 , wherein the therapeutic property improves the ability to remove the wound dressing from a wound.

19 . The wound treatment system of claim 1 , wherein the therapeutic property reduces biofilm buildup in a wound.

20 . (canceled)

21 . (canceled)

22 . (canceled)

23 . (canceled)

24 . (canceled)

25 . (canceled)

26 . (canceled)

27 . A method of treating a wound, the method comprising:
applying a wound dressing to the wound; transporting fluid through a conduit to the wound dressing, wherein the fluid comprises molecules having a coating comprising an ultraviolet-activated protective material adapted to be partially broken down while traveling through the conduit; and directing energy to the fluid proximal to the wound dressing to degrade the coating.

28 . The method of claim 27 , wherein degrading the coating activates a therapeutic property of the fluid.

29 . The method of claim 28 , wherein the therapeutic property includes an anti-biotic property.

30 . The method of claim 28 , wherein the therapeutic property includes an analgesic property.

31 . The method of claim 28 , wherein the therapeutic property aids with debridement of tissue.

32 . The method of claim 28 , wherein the therapeutic property improves the ability to remove the wound dressing from a wound.

33 . The method of claim 28 , wherein the therapeutic property reduces biofilm buildup in a wound.

34 . (canceled)

35 . (canceled)

36 . (canceled)

37 . (canceled)

38 . (canceled)

39 . A wound treatment system comprising:
a wound dressing; a fluid storage device in fluid communication with the wound dressing; a fluid comprising molecules with at least one type of therapeutic agent, wherein the molecules are constructed so that the therapeutic agent is inhibited by a light-sensitive branch which when broken thereby activates the therapeutic agent; and an energy source configured to direct energy to the fluid and to control the light-sensitive branch of the molecules of the fluid.

40 . The wound treatment system of claim 39 , wherein the fluid comprises an anti-microbial agent.

41 . The wound treatment system of claim 40 , wherein the anti-microbial agent is hypochlorous acid (HOCl) or hypochlorite ion (ClO − ).

42 . (canceled)

43 . (canceled)

44 . (canceled)

45 . (canceled)

46 . The wound treatment system of claim 39 , wherein the fluid comprises molecules having an active agent that is a clotting agent.

47 . The wound treatment system of claim 46 , wherein the clotting agent is a trivalent salt, such as Fe +++ or Al +++ .

48 . The wound treatment system of claim 47 , wherein the Fe +++ compound is encapsulated in a glucose sensitive microcapsule, which increases in permeability to allow for the release of the Fe +++ agent upon encountering glucose.

49 . The wound treatment system of claim 39 , wherein the fluid comprises multiple agents which are activated by different wavelengths of light or frequencies of energy.

Assignees

• Kci Licensing Inc

Inventors

• Locke Christopher Brian
• Robinson Timothy Mark
• Coulthard Richard Daniel John

Classifications

• A61P31/00

  Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

• A61M2205/0272

  Electro-active or magneto-active materials · CPC title

• A61L15/18

  containing inorganic materials · CPC title

• A61L15/64

  specially adapted to be resorbable inside the body · CPC title

• A61N5/02

  using microwaves · CPC title