Antimicrobial composition

Patent metadata

Field	Value
Publication number	US-2017231220-A1
Application number	US-201715586030-A
Country	US
Kind code	A1
Filing date	May 3, 2017
Priority date	Nov 25, 2013
Publication date	Aug 17, 2017
Grant date	—

Abstract

An anti-microbial composition including: a solvent; a cationic active ingredient; a source of zinc ions, wherein the zinc ions have a concentration from 6.2×10 −4 to 8.7×10 −3 mol/L; and an amine oxide surfactant. A method of selectively killing Gram-positive bacteria, the method including: exposing bacteria to a formulation including: 0.05 to 0.3 wt. % of benzethonium chloride and/or benzalkonium chloride; a source of zinc ions, wherein the zinc ions have a concentration from 6.8×10 −3 to 2×10 −2 mol/L; and an amine oxide surfactant.

First claim

What is claimed is:

1 . An antimicrobial composition, comprising:
a solvent; a cationic active ingredient; a source of zinc ions, wherein the zinc ions have a concentration from 6.2×10 −4 to 8.7×10 −3 mol/L; and an amine oxide surfactant.

2 . The antimicrobial composition of claim 1 , in which the zinc ions have a concentration from 2.5×10 −3 to 6.8×10 −3 mol/L.

3 . The antimicrobial composition of claim 1 , in which the zinc ions have a concentration from 3.1×10 −3 to 6.2×10 −3 mol/L.

4 . The antimicrobial composition of claim 1 , in which the source of zinc ions is zinc sulfate.

5 . The antimicrobial composition of claim 1 , in which the cationic active ingredient comprises benzethonium chloride.

6 . The antimicrobial composition of claim 1 , in which the cationic active ingredient comprises benzalkonium chloride.

7 . The antimicrobial composition of claim 1 , further comprising 0.5 to 3 wt. % of the composition of cetrimonium chloride.

8 . The antimicrobial composition of claim 1 , wherein the amine oxide surfactant comprises 0.9 to 1.9 wt. % of the composition of lauryldimethylamine oxide.

9 . The antimicrobial composition of claim 1 , further comprising a chelating agent, wherein the chelating agent is an organic polyacid.

10 . The antimicrobial composition of claim 1 , further comprising a non-ionic surfactant, the non-ionic surfactant comprising a polyether with at least 10 ether units.

11 . The antimicrobial composition of claim 1 , further comprising a cosurfactant, wherein the cosurfactant comprises: cocamidopropyl betaine, sunfloweramidopropyl ethonium sulfate, PEG-120 methyl glucose dioleate, lauryl/myristyl amidopropyl amine oxide, lauramidopropylamine oxide, or combinations thereof.

12 . The antimicrobial composition of claim 1 , further comprising a dye, a fragrance, a preservative, a pH adjuster, an antiseptic, a humectant, or combinations thereof.

13 . The antimicrobial composition of claim 1 , wherein the composition achieves an at least 5 log 10 reduction of living E. coli bacteria within 15 seconds of exposure of the bacteria to the composition.

14 . An antimicrobial product, comprising:
a container and an antimicrobial composition housed within the container, wherein the antimicrobial composition comprises:
a quaternary ammonium compound, wherein at least one substitution on the amine comprises a aromatic ring, the quaternary ammonium compound comprising 0.05 to 0.30 wt. % of the composition;
a zinc salt, wherein the zinc ions have a concentration from 1.5×10 −3 to 7.7×10 −3 mol/L;
an amine oxide surfactant, comprising 0.5 to 3 wt. % of the antimicrobial composition;
cetrimonium chloride; and
a polar solvent.

15 . The product of claim 14 , wherein the polar solvent comprises an alcohol with no more than five carbon atoms per molecule.

16 . The product of claim 14 , wherein the polar solvent comprises water and water comprises no less than 80 wt. % of the antimicrobial composition.

17 . The product of claim 14 , in which the antimicrobial composition produces at least 4 log 10 reductions in a Gram-negative bacteria population over a 30 second exposure.

18 . The product of claim 14 , in which the antimicrobial composition further comprises a thickening agent.

19 . The product of claim 14 , in which the quaternary ammonium compound comprises benzethonium chloride.

20 . A method of selectively killing Gram-positive bacteria, the method comprising:
exposing bacteria to a formulation comprising:
0.05 to 0.3 wt. % of benzethonium chloride and/or benzalkonium chloride;
a source of zinc ions, wherein the zinc ions have a concentration from 6.8×10 −3 to 2×10 −2 mol/L; and
an amine oxide surfactant.

21 . The method of claim 20 , further comprising rinsing the formulation from the bacteria after exposure.

22 . The method of claim 20 , wherein the amine oxide surfactant comprises 0.5 wt. % to 3 wt. % of the formulation.

Assignees

• Henkel IP & Holding GmbH

Inventors

• Lawshe Jessica
• Fuls Janice L
• Cole Gregory
• Rodgers Nancy D

Classifications

• A61K8/27

  Zinc; Compounds thereof · CPC title

• A01N59/16

  Heavy metals; Compounds thereof · CPC title

• A61K2800/74

  Biological properties of particular ingredients · CPC title

• A61K8/416

  Quaternary ammonium compounds (A61K8/35 takes precedence) · CPC title

• A01N33/12 Primary

  Quaternary ammonium compounds · CPC title