Systems and methods for multiple analyte analysis

Patent metadata

Field	Value
Publication number	US-2017191958-A1
Application number	US-201715465717-A
Country	US
Kind code	A1
Filing date	Mar 22, 2017
Priority date	Nov 2, 2012
Publication date	Jul 6, 2017
Grant date	—

Abstract

Systems and methods for multiple analyte analysis are provided. In one embodiment, a method includes determining concentrations of first and second analytes in a sample. The first and second analytes may be, for example, glucose and hydroxybutyrate. In this form, an indication related to the measured concentration of hydroxybutyrate is provided in response to determining that the concentration of hydroxybutyrate is above a predetermined value. In a further aspect of this form, a quantitative indication representative of the measured glucose concentration is automatically provided regardless of the value of the measured glucose concentration. In another embodiment, a system includes a meter configured to interact with a test element to assess first and second analytes in a sample. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings.

First claim

The invention claimed is:

1 . A method of analyzing multiple analytes in a sample, the method comprising the steps of:
contacting a test element with the sample, wherein the test element is configured for electrochemically analyzing first and second analytes, respectively, in the sample, and wherein the first analyte is a ketone and the second analyte is glucose; determining a first analyte concentration and a second analyte concentration in the sample via a test meter configured to interact with the test element; and providing an indication related to the first analyte concentration in response to determining the first analyte concentration is above a predetermined value and automatically providing an indication related to the second analyte concentration.

2 . The method of claim 1 , wherein the predetermined value is in a range of about 0.5 mM to about 3.0 mM.

3 . The method of claim 2 , wherein the predetermined value is about 0.6 mM.

4 . The method of claim 1 , wherein the step of providing the indication related to the first analyte concentration in response to determining the first analyte concentration is above the predetermined value includes at least one of displaying the first analyte concentration, providing a warning, providing a list of actions to take in response to the first analyte concentration being above the first predetermined value, and transmitting a message to at least one of a user of the test element, healthcare provider, caregiver and parent or guardian.

5 . The method of claim 1 , wherein the step of providing the indication related to the first analyte concentration in response to determining the first analyte concentration is above the predetermined value includes transmitting a message to a mobile device or computer.

6 . The method of claim 5 further comprising displaying a message related to the first analyte concentration on the test meter.

6 . The method of claim 1 , wherein the step of providing the indication related to the first analyte concentration in response to determining the first analyte concentration is above the predetermined value includes displaying a message related to the first analyte concentration on the test meter.

7 . The method of claim 1 , wherein the step of providing the indication related to the first analyte concentration in response to determining the first analyte concentration is above the predetermined value includes changing a color of at least a portion of a display screen of the test meter.

8 . The method of claim 1 , wherein the step of providing the indication related to the first analyte concentration in response to determining the first analyte concentration is above the predetermined value includes displaying an information icon on a display screen of the test meter.

9 . The method of claim 8 further comprising providing a message in response to a selection of the information icon.

10 . The method of claim 9 , wherein the message includes at least one of a description of the first analyte concentration, a list of actions to take in response to the first analyte concentration being above the first predetermined value, and contact information of a healthcare provider.

11 . The method of claim 1 , wherein the step of automatically providing the indication related to the second analyte concentration includes at least one of displaying the second analyte concentration, providing a warning, providing a list of actions to take in response to the second analyte concentration, and transmitting a message to at least one of a user of the test element, healthcare provider, caregiver and parent or guardian.

12 . The method of claim 1 , wherein the step of determining the first analyte concentration and the second analyte concentration is completed within 10 seconds after contacting the test element with the sample.

13 . The method of claim 12 , wherein the step of determining the first analyte concentration and the second analyte concentration is completed within 7.5 seconds after contacting the test element with the sample.

14 . The method of claim 12 , wherein the step of determining the first analyte concentration and the second analyte concentration is completed within 5 seconds after contacting the test element with the sample.

15 . The method of claim 1 , wherein the ketone is hydroxybutyrate.

16 . A method of analyzing multiple analytes in a sample, the method comprising the steps of:
contacting a test element with the sample, wherein the test element is configured for electrochemically analyzing first and second analytes, respectively, in the sample, and wherein the first analyte is a ketone and the second analyte is glucose; determining a first analyte concentration and a second analyte concentration in the sample via a test meter configured to interact with the test element; and providing an indication related to the first analyte concentration in response to determining the first analyte concentration is above a predetermined value.

17 . The method of claim 16 further comprising the step of:
storing one or both of the first analyte concentration and the second analyte concentration, and wherein the step of providing the indication further comprises providing an indication related to the second analyte concentration upon user access to the stored second analyte concentration.

18 . The method of claim 16 , wherein the step of determining the first analyte concentration and the second analyte concentration is completed within 10 seconds after contacting the test element with the sample.

19 . The method of claim 16 , wherein the predetermined value is in a range of about 0.5 mM to about 3.0 mM.

20 . The method of claim 16 , wherein the ketone is hydroxybutyrate.

Assignees

• Roche Diabetes Care Inc

Inventors

• Gerber Martin T
• Diebold Eric

Classifications

• A61B5/0002 Primary

  Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07) · CPC title

• A61B2562/0295

  Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 · CPC title

• G01N33/492 Primary

  Determining multiple analytes · CPC title

• A61B5/1486

  using enzyme electrodes, e.g. with immobilised oxidase · CPC title

• G01N27/307 Primary

  Disposable laminated or multilayered electrodes (G01N27/3272 takes precedence) · CPC title