System and method for providing stable fluid flow

Patent metadata

Field	Value
Publication number	US-2017191922-A1
Application number	US-201615373722-A
Country	US
Kind code	A1
Filing date	Dec 9, 2016
Priority date	Dec 30, 2015
Publication date	Jul 6, 2017
Grant date	—

Abstract

An embodiment of a system with a minute measure of pulsatility in a flow of a fluid is described that comprises a first pump configured to flow the fluid to a junction at a first flow rate that comprises a measure of pulsatility; and a second pump configured to flow a portion of the fluid from the junction at a second flow rate that is less than the first flow rate to produce a flow of the fluid at a third flow rate from the junction with a minute measure of pulsatility.

First claim

What is claimed is:

1 . A system with a minute measure of pulsatility in a flow of a fluid, comprising:
a first pump configured to flow the fluid to a junction at a first flow rate that comprises a measure of pulsatility; and a second pump configured to flow a portion of the fluid from the junction at a second flow rate that is less than the first flow rate to produce a flow of the fluid at a third flow rate from the junction with a minute measure of pulsatility.

2 . The system of claim 1 wherein the second flow rate is slower than the first flow rate.

3 . The system of claim 1 wherein the first pump comprises a gear pump.

4 . The system of claim 3 wherein the first pump comprises small teeth.

5 . The system of claim 3 wherein the first pump operates at 1000 RPM.

6 . The system of claim 3 wherein the second pump comprises a gear pump.

7 . The system of claim 5 the first pump comprises small teeth.

8 . The system of claim 3 wherein the second pump operates at 990 RPM.

9 . The system of claim 1 wherein the flow rates of the first and second pumps are adjustable.

10 . The system of claim 1 wherein the fluid flowing at the third flow rate enters a detection region.

11 . The system of claim 10 wherein the detection region comprises a flow cell.

12 . The system of claim 1 wherein a sample fluid is introduced to the fluid flowing at the third flow rate.

13 . The system of claim 12 wherein the combined sample fluid and the fluid flowing at the third flow rate become a single flow, wherein the sample fluid forms a core diameter portion of the single flow and the fluid flowing at the third flow rate comprises a sheath portion of the single flow.

14 . The system of claim 13 wherein the single flow flows at a fourth flow rate.

15 . The system of claim 14 wherein a third pump produces the fourth flow rate that is greater than the third flow rate, wherein the third pump draws the sample fluid into the fluid flowing at the third flow rate.

16 . A method for providing a fluid flow with a minute measure of pulsatility, comprising:
flowing a fluid to a junction at a first flow rate that comprises a measure of pulsatility; and flowing a portion of the fluid from the junction at a second flow rate that is less than the first flow rate to produce a third flow rate of the fluid from the junction with a minute measure of pulsatility.

17 . The method of claim 16 wherein the fluid flowing at the third flow rate enters a detection region.

18 . The method of claim 16 wherein a sample fluid is introduced to the fluid flowing at the third flow rate.

19 . The method of claim 18 wherein the combined sample fluid and the fluid flowing at the third flow rate become a single flow, wherein the sample fluid forms a core diameter portion of the single flow and the fluid flowing at the third flow rate comprises a sheath portion of the single flow.

20 . The method of claim 19 wherein the single flow flows at a fourth flow rate.

Assignees

• Life Technologies Corp

Inventors

• Ward Michael
• Malkin Jason

Classifications

• F04C2270/80

  Diagnostics · CPC title

• F04C15/0049

  Equalization of pressure pulses (silencing for compressors F04C29/06) · CPC title

• F04C2270/145

  Controlled or regulated · CPC title

• F04B49/065

  and making use of computers · CPC title

• F04C2270/44

  Conditions at the outlet of a pump or machine · CPC title