Use of a Measuring Appliance for Examining Constituents of a Human or Animal Body

Patent metadata

Field	Value
Publication number	US-2017176549-A1
Application number	US-201615383186-A
Country	US
Kind code	A1
Filing date	Dec 19, 2016
Priority date	Dec 21, 2015
Publication date	Jun 22, 2017
Grant date	—

Abstract

The use of a hand-held, energy-independent measuring appliance comprising a housing, in which provision is made of at least a nuclear magnetic resonance sensor, a control apparatus for controlling the measuring appliance, an evaluation apparatus for evaluating a measurement signal supplied by the nuclear magnetic resonance sensor, an output apparatus for outputting ascertained information and an apparatus for energy supply for the measuring appliance in the form of a battery, in particular a rechargeable battery, for the purposes of examining a constituent of a human or animal body, in particular for examining tissue and/or bodily fluids, preferably for examining blood and/or urine, is proposed.

First claim

What is claimed is:

1 . A method of examining a constituent of at least one of a human body and an animal body, the method comprising:
examining the constituent of the at least one of the human body and the animal body using a hand-held, energy-independent measuring appliance, the measuring appliance including a (i) housing, (ii) a nuclear magnetic resonance sensor arranged in the housing, (iii) a control apparatus arranged in the housing and configured to control the measuring appliance, (iv) an evaluation apparatus arranged in the housing and configured to evaluate a measurement signal supplied by the nuclear magnetic resonance sensor, (v) an output apparatus arranged in the housing and configured to output ascertained information, and (vi) a rechargeable battery arranged in the housing and configured to supply energy.

2 . The method according to claim 1 , further comprising:
evaluating, using the evaluation apparatus, at least one of a spectrum and a relaxation time of the measurement signal supplied by the nuclear magnetic resonance sensor resulting from the excitation of nuclear spins in the constituent by way of the nuclear magnetic resonance sensor.

3 . The method according to claim 2 , further comprising:
comparing, using the evaluation apparatus, the at least one of the spectrum and the relaxation time with reference data from a reference database.

4 . The method according to claim 2 , further comprising:
displaying, using the output apparatus, at least one of (i) the at least one of the spectrum and the relaxation time and (ii) a deviation of the at least one of the spectrum and the relaxation time from reference data from a reference database.

5 . The method of according to claim 1 , the examining of the constituent further comprising:
examining, using the measuring appliance, the constituent with spatial resolution.

6 . The method of according to claim 1 , further comprising:
specifying, with user inputs to an input apparatus that are made available to the measuring appliance, specifications relating to the constituent.

7 . The method of according to claim 1 , further comprising:
calibrating the measuring appliance, before the examining of the constituent, using a standard sample provided within the measuring appliance.

8 . A hand-held, energy-independent measuring appliance, the measuring appliance comprising:
a housing; a nuclear magnetic resonance sensor arranged in the housing; a control apparatus arranged in the housing and configured to control the measuring appliance; an evaluation apparatus arranged in the housing and configured to evaluate a measurement signal supplied by the nuclear magnetic resonance sensor; an output apparatus arranged in the housing and configured to output ascertained information; and a rechargeable battery arranged in the housing and configured to supply energy wherein the measuring appliance is configured to examine examining a constituent of at least one of a human body and animal body.

9 . Method for examining a constituent of at least one of a human body and animal body using a hand-held, energy-independent measuring appliance, the measuring appliance including a (i) housing, (ii) a nuclear magnetic resonance sensor arranged in the housing, (iii) a control apparatus arranged in the housing and configured to control the measuring appliance, (iv) an evaluation apparatus arranged in the housing and configured to evaluate a measurement signal supplied by the nuclear magnetic resonance sensor, (v) an output apparatus arranged in the housing and configured to output ascertained information, and (vi) a rechargeable battery arranged in the housing and configured to supply energy, the method comprising:
specifying, using an input apparatus, specifications relating to the constituent; calibrating the nuclear magnetic resonance sensor using a standard sample provided within the appliance; placing at least one of (i) the measuring appliance against the constituent and (ii) the constituent against the measuring appliance; measuring at least one of a spectrum and a relaxation time resulting from an excitation of nuclear spins in the constituent; evaluating measurement signals from the nuclear magnetic resonance sensor by comparing the measurement signals with reference data from a reference database; and outputting results of the evaluation of the measurement signals.

10 . The method according to claim 1 , wherein the constituent is at least one of tissue and bodily fluids of the at least one of the human body and the animal body.

11 . The method according to claim 1 , wherein the constituent is at least one of blood and urine of the at least one of the human body and the animal body.

12 . The method according to claim 4 , wherein the output apparatus is a display.

13 . The method according to claim 5 , the examining of the constituent further comprising:
examining, using the measuring appliance, the constituent with at least one of position resolution and depth resolution.

14 . The method according to claim 7 , wherein the standard sample provided within the measuring appliance is a tetramethylsilane sample.

15 . The measuring appliance according to claim 8 , wherein the constituent is at least one of tissue and bodily fluids of the at least one of the human body and the animal body.

16 . The measuring appliance according to claim 8 , wherein the constituent is at least one of blood and urine of the at least one of the human body and the animal body.

17 . The method according to claim 9 , wherein the constituent is at least one of tissue and bodily fluids of the at least one of the human body and the animal body.

18 . The method according to claim 9 , wherein the constituent is at least one of blood and urine of the at least one of the human body and the animal body.

19 . The method according to claim 9 , wherein the standard sample provided within the measuring appliance is a tetramethylsilane sample.

20 . The method according to claim 9 , the outputting of the results of the evaluation of the measurement signals further comprising:
outputting at least one of (i) ascertained information and (ii) a deviation of the ascertained information from the reference data of the reference database.

Assignees

• Bosch Gmbh Robert

Inventors

• Krapf Reiner
• Hoffmann Ulli
• Graessl Andreas
• Marx Klaus

Classifications

• A61B5/055

  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging · CPC title

• G01R33/46

  NMR spectroscopy · CPC title

• G01R33/448 Primary

  Relaxometry, i.e. quantification of relaxation times or spin density (G01R33/50 takes precedence) · CPC title

• G01R33/28 Primary

  Details of apparatus provided for in groups G01R33/44 - G01R33/64 · CPC title

• G01R33/483

  with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy · CPC title