Seeping flow anti-clotting blood catheter

Patent metadata

Field	Value
Publication number	US-2017100564-A1
Application number	US-201514595938-A
Country	US
Kind code	A1
Filing date	Jan 13, 2015
Priority date	Jan 14, 2014
Publication date	Apr 13, 2017
Grant date	—

Abstract

The device and methods described herein relate to a seeping flow catheter. The seeping flow catheter includes a porous material. The inner face of the porous material defines the lumen of the catheter. The porous material is configured such that fluid can flow along the length of the catheter, between the inner face and outer face of the porous material. As the fluid flows through the porous material, the fluid can seep into the lumen of the catheter through the inner face or out of the catheter through the outer face of the porous material. Portions of the inner or outer face can include a lining that substantial reduces the perfusion of the fluid through the lined areas.

First claim

What is claimed:

1 . A catheter comprising:
an elongated tube having a distal end and a proximal end, the elongated tube comprising: a porous material having an interior face and an exterior face, the interior face defining a lumen along a central axis of the elongated tube, wherein the porous material is configured to flow a fluid between the interior face and the exterior face of the porous material and to seep the fluid out of the porous material through the exterior face and interior face; and a first lining covering at least a portion of the exterior face and substantially limiting a perfusion through the exterior face at the portion of the exterior face covered by the first lining.

2 . The catheter of claim 1 , further comprising a fitting coupled to the proximal end of the elongated tube, the fitting configured to flow a first fluid into the porous material and a second fluid into the lumen.

3 . The catheter of claim 2 , wherein the first fluid is different than the second fluid.

4 . The catheter of claim 1 , wherein the resistance to flow through the inner face or exterior face of the porous material is between about 10 and about 100 time higher than the resistance to flow through the porous material along an axis parallel to the central axis of the elongated tube.

5 . The catheter of claim 1 , further comprising a second lining covering at least a portion of the interior face.

6 . The catheter of claim 5 , wherein the second lining covers substantially all of the interior face except a portion toward the distal end of the elongated tube.

7 . The catheter of claim 1 , wherein the first lining covers substantially all of the exterior face except a portion toward the distal end of the elongated tube.

8 . The catheter of claim 1 , further comprising a second lining covering at least a portion of the exterior face and having a porosity greater than the first lining.

9 . The catheter of claim 1 , wherein the thickness of the porous material is between about 20 μm and about 1 mm.

10 . The catheter of claim 1 , wherein the porous material comprises phase inversion polyethersulfone.

11 . The catheter of claim 1 , where in the interior face has a first porosity at a first distance from the proximal end of the elongated tube and a second porosity at a second distance from the proximal end of the elongated tube.

12 . A method comprising:
providing a catheter comprising a porous material having an interior face and an exterior face, the interior face of the catheter defining a central lumen; flowing a first fluid through the porous material of the catheter; flowing a second fluid through the central lumen of the catheter; and seeping the first fluid into the central lumen of the catheter through the interior face of the catheter.

13 . The method of claim 12 , further comprising flowing an anti-coagulant through the porous material of the catheter.

14 . The method of claim 12 , further comprising flowing the first fluid through the porous material at a pressure configured to force the first fluid to seep through the interior face of the catheter and into the central lumen of the catheter.

15 . The method of claim 12 , further comprising flowing a first agent through the central lumen of the catheter.

16 . The method of claim 15 , further comprising flowing a second agent, which counteracts the first agent, through the porous material of the catheter.

17 . The method of claim 12 , wherein the first fluid is different than the second fluid.

18 . The method of claim 12 , wherein the porous interior face has a first porosity at a first distance from an inlet of the catheter and a second porosity at a second distance from the inlet of the catheter.

19 . The method of claim 12 , wherein the first fluid is flowed through porous material at a pulsatile flow rate.

20 . The method of claim 12 , further seeping the first fluid out of the catheter through the external face of the porous material.

21 . The method of claim 12 , wherein the porous material of the catheter comprises phase inversion polyethersulfone.

Assignees

• Charles Stark Draper Laboratory Inc

Inventors

• Charest Joseph L
• Hsiao James
• Dibiasio Christopher
• Hufford Kevin A

Classifications

• A61M2025/006

  having a special surface topography or special surface properties, e.g. roughened or knurled surface · CPC title

• A61M2025/0057

  Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings · CPC title

• A61M25/0043 Primary

  characterised by structural features · CPC title

• A61M25/0029 Primary

  characterized by features relating to least one lumen located at the middle part of the catheter, e.g. slots, flaps, valves, cuffs, apertures, notches, grooves or rapid exchange ports (catheter shaft surface irregularities A61M2025/006) · CPC title

• A61M2205/3334

  Measuring or controlling the flow rate · CPC title