Articles and methods comprising persistent carbenes and related compositions

Patent metadata

Field	Value
Publication number	US-2016355484-A1
Application number	US-201615171998-A
Country	US
Kind code	A1
Filing date	Jun 2, 2016
Priority date	Mar 13, 2013
Publication date	Dec 8, 2016
Grant date	—

Abstract

Articles and methods comprising persistent carbenes are provided, as well as related compositions. In some embodiments, a persistent carbene may be associated with a portion of a substrate (e.g., at least a portion of a surface on the substrate). In certain embodiments, the association of persistent carbene with the substrate may be used to affect certain properties of substrate (e.g., surface chemistry, stability). In some cases, a persistent carbene may be functionalized after association with a portion of a substrate. In some embodiments, a persistent carbene and at least one secondary compound may be associated with a portion of a substrate. Articles and methods of the present invention may be useful for applications involving electronics, sensing, microfabrication, nanotechnology, biomimetic, and drug delivery, amongst others.

First claim

1 - 21 . (canceled)

22 . An article, comprising:
a substrate having a surface, wherein at least a portion of the surface is associated with a plurality of persistent carbenes and a plurality of secondary compounds, wherein each of the plurality of the persistent carbenes and each of the plurality of the secondary compounds comprise at least one functionalizable group.

23 . The article of claim 22 , wherein the secondary compound comprises a thiol, thioether, selenol, dithiocarbamate, dithioate, dithiophosphinate, phosphonate, carboxylic acid and carboxylate group, amino, aminoacyl, pyridine, phosphine, alcohol, alkoxy, nitrile, isocyanide, alkyl, alkenyl, aryl, or alkynyl group.

24 . The article of claim 22 , wherein the secondary compound is associated with the surface via the thiol, thioether, selenol, dithiocarbamate, dithioate, dithiophosphinate, phosphonate, carboxylic acid and carboxylate group, amino, aminoacyl, pyridine, phosphine, alcohol, alkoxy, nitrile, isocyanide, alkyl, alkenyl, aryl, or alkynyl.

25 . The article of claim 22 , wherein the substrate comprises a metal, metalloid, an organic material, a non-metal, or combinations thereof.

26 . The article of claim 22 , wherein the portion of the substrate comprises gold.

27 . The article of claim 22 , wherein the substrate comprises a plurality of particles.

28 . The article of claim 22 , wherein the plurality of persistent carbenes and/or plurality of secondary compounds form a monolayer on at least one surface of the substrate.

29 . A sensor comprising the article of claim 22 .

30 - 44 . (canceled)

Assignees

• Massachusetts Inst Technology

Inventors

• Johnson Jeremiah A
• Zhukhovitskiy Aleksandr V

Classifications

• C07D233/20 Primary

  with substituted hydrocarbon radicals, directly attached to ring carbon atoms · CPC title

• C07D403/10

  linked by a carbon chain containing aromatic rings · CPC title

• C07D403/14

  containing three or more hetero rings · CPC title

• C07D233/06

  with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms · CPC title

• C08F292/00

  Macromolecular compounds obtained by polymerising monomers on to inorganic materials · CPC title