Compounds, compositions, and methods for the treatment of inflammatory, degenerative, and neurodegenerative diseases
US-2024409487-A1 · Dec 12, 2024 · US
US2016355456A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016355456-A1 |
| Application number | US-201615239908-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 18, 2016 |
| Priority date | Sep 26, 2007 |
| Publication date | Dec 8, 2016 |
| Grant date | — |
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An object of the present invention is to provide a plant extract which comprises o-diphenol type chlorogenic acids in a high concentration. Also, it is to provide a plant extract excellent in deodorizing property or anti-oxidation property, which does not substantially comprise ferulylquinic acids and caffeine content. The present invention provides a plant extract, which comprises chlorogenic acids comprising an o-diphenol type chlorogenic acid and does not substantially comprise ferulylquinic acid and caffeine, which is excellent in deodorizing property or anti-oxidation property.
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1 . A method for producing a plant extract which comprises chlorogenic acids comprising an o-diphenol chlorogenic acid and ferulylquinic acid and caffeine, wherein the ferulyquinic acid is contained in an amount of less than 0.3% by mass based on the total amount of the plant extract and the caffeine is contained in an amount of less than 0.1% by mass based on the total amount of the plant extract, wherein the method comprises at least a step of subjecting a plant comprising a chlorogenic acid to an extraction treatment using water or a hydrous water miscible organic solvent, a step of subjecting the aforementioned extraction treated matter to a contact treatment with a synthetic resin adsorbent, and a step of concentrating the unadsorbed solution on synthetic resin adsorbent obtained by the aforementioned contact treatment step. 2 . The method for producing a plant extract according to claim 1 , wherein the step of subjecting the extraction treated matter to a contact treatment with a synthetic resin adsorbent is a step of subjecting the extraction treated matter to a contact treatment with a synthetic resin adsorbent using a column method. 3 . The method for producing a plant extract according to claim 2 , which further comprises a step of removing the extraction solvent from the extract obtained by the extraction treatment step and a step of diluting the aforementioned solvent-removed matter again with the solvent. 4 . The method for producing a plant extract according to claim 2 , wherein a specific gravity of the solvent-removed matter is 1.06 or more and the solvent-removed matter is diluted with the solvent to have a Brix value of from 3 to 50. 5 . The method for producing a plant extract according to claim 3 , wherein a specific gravity of the solvent-removed matter is 1.06 or more and the solvent-removed matter is diluted with the solvent to have a Brix value of from 3 to 50. 6 . The method for producing a plant extract according to claim 2 , wherein, in the step of subjecting the extraction treated matter to a contact treatment with a synthetic resin adsorbent using a column method, the contact treatment temperature is 60° C. or less, amount of the adsorbent to be packed in the column is 3 times (by mass) or more based on a solid content of the solvent extract and space velocity (SV value) of the solvent extract passing through the column is 2 or less. 7 . The method for producing a plant extract according to claim 3 , wherein, in the step of subjecting the extraction treated matter to a contact treatment with a synthetic resin adsorbent using a column method, the contact treatment temperature is 60° C. or less, amount of the adsorbent to be packed in the column is 3 times (by mass) or more based on a solid content of the solvent extract and space velocity (SV value) of the solvent extract passing through the column is 2 or less. 8 . The method for producing a plant extract according to claim 4 , wherein, in the step of subjecting the extraction treated matter to a contact treatment with a synthetic resin adsorbent using a column method, the contact treatment temperature is 60° C. or less, amount of the adsorbent to be packed in the column is 3 times (by mass) or more based on a solid content of the solvent extract and space velocity (SV value) of the solvent extract passing through the column is 2 or less. 9 . The method for producing a plant extract according to claim 5 , wherein, in the step of subjecting the extraction treated matter to a contact treatment with a synthetic resin adsorbent using a column method, the contact treatment temperature is 60° C. or less, amount of the adsorbent to be packed in the column is 3 times (by mass) or more based on a solid content of the solvent extract and space velocity (SV value) of the solvent extract passing through the column is 2 or less.
Free radical scavengers or antioxidants · CPC title
Extraction of the material · CPC title
Plant extracts, their artificial duplicates or their derivatives · CPC title
Adding ingredients (adding preservatives A23B70/10) · CPC title
of unsaturated hydroxy carboxylic acids · CPC title
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