Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
US-2024337668-A1 · Oct 10, 2024 · US
Assessing neuronal damage from blood samples
US2016349272A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016349272-A1 |
| Application number | US-201414550240-A |
| Country | US |
| Kind code | A1 |
| Filing date | Nov 21, 2014 |
| Priority date | Mar 31, 2003 |
| Publication date | Dec 1, 2016 |
| Grant date | — |
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Abstract
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Neuronal damage is detected by providing a biological sample derived from the subject, detecting in the sample the presence of a neurofilament subunits or their breakdown products, and correlating the presence and level of the neurofilament subunits and their breakdown products detected with the degree of neuronal injury.
First claim
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1 . A method of detecting neuronal injury in a subject's central nervous system (CNS), the method comprising the steps of: (a) providing a blood, serum, or plasma sample from the subject; (b) contacting the blood, serum, or plasma sample with an antibody that specifically binds to NF-H in the sample; (c) detecting the presence or amount of NF-H in the sample, wherein NF-H can be detected in quantities as low as 50 pg in 50 μl; and (d) correlating the presence or amount of NF-H in the samp…
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- G01N33/6896Primary
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US2016349272A1 cover?
- Neuronal damage is detected by providing a biological sample derived from the subject, detecting in the sample the presence of a neurofilament subunits or their breakdown products, and correlating the presence and level of the neurofilament subunits and their breakdown products detected with the degree of neuronal injury.
- Who is the assignee on this patent?
- Univ Florida
- What technology area does this patent fall under?
- Primary CPC classification G01N33/6896. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Thu Dec 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).