Methods and compositions for treating melanoma
US-2024424002-A1 · Dec 26, 2024 · US
Cadherins as Cancer Biomarkers
US2016349264A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016349264-A1 |
| Application number | US-201615236851-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 15, 2016 |
| Priority date | Sep 28, 2011 |
| Publication date | Dec 1, 2016 |
| Grant date | — |
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Abstract
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Methods of isolating, enriching, capturing, identifying, or detecting the presence of, cancerous cells in a sample, e.g., a blood sample from a subject, by detecting the presence of one or more cancer cell surface markers selected from the group consisting of cadherin 1 (CDH1), CDH2, CDH3, CDH4, CDH5, CDH9, CDH11, CDH17, CDH19, protocadherin 9 (PCDH9) and/or PCDH beta 13 (PCDHb13), and optionally an additional cancer cell surface marker, e.g., EpCAM, MUC1, EphB4, EGFR, CEA, and/or HER2.
First claim
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What is claimed is: 1 . A method of detecting the presence of a circulating tumor cell (CTC) in a sample from a subject, the method comprising: providing a sample comprising blood from a subject; and contacting the sample with one or more agents that bind to a cancer cell surface marker selected from the group consisting of cadherin 1 (CDH1), CDH2, CDH3, CDH4, CDH5, CDH9, CDH11, CDH17, CDH19, protocadherin 9 (PCDH9) and/or PCDH beta 13 (PCDHb13); and detecting the binding of…
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Classifications
- G01N33/5759Primary
Physics · mapped topic
Physics · mapped topic
- G01N33/57492Primary
Physics · mapped topic
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- What does patent US2016349264A1 cover?
- Methods of isolating, enriching, capturing, identifying, or detecting the presence of, cancerous cells in a sample, e.g., a blood sample from a subject, by detecting the presence of one or more cancer cell surface markers selected from the group consisting of cadherin 1 (CDH1), CDH2, CDH3, CDH4, CDH5, CDH9, CDH11, CDH17, CDH19, protocadherin 9 (PCDH9) and/or PCDH beta 13 (PCDHb13), and optional…
- Who is the assignee on this patent?
- Massachusetts Gen Hospital
- What technology area does this patent fall under?
- Primary CPC classification G01N33/5759. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Thu Dec 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).