Crystalline materials on biological tissue and methods for making the same
US-2015368632-A1 · Dec 24, 2015 · US
US2016348075A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016348075-A1 |
| Application number | US-201615236266-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 12, 2016 |
| Priority date | Feb 14, 2014 |
| Publication date | Dec 1, 2016 |
| Grant date | — |
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The present invention relates to an immortalized cell, an immortalized cell line comprising said immortalized cell, a cell culture comprising the immortalized cell or cell line, and a method for the production of an immortalized cell.
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Therefore, what is claimed is: 1 . Immortalized periosteum cell. 2 . Immortalized periosteum cell of claim 1 , which is a human immortalized periosteum cell. 3 . Immortalized periosteum cell of claim 1 , which is an immortalized cranium periosteum cell. 4 . Immortalized periosteum cell of claim 1 , which is osteogenically differentiable. 5 . Immortalized periosteum cell of claim 1 , which was deposited on 29 Nov. 2013 under the designation “Tag58” at the Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Braunschweig, Germany (DSMZ) under the accession number DSM ACC3218. 6 . Immortalized periosteum cell line, which comprises the periosteum cell of claim 1 . 7 . Cell culture, which comprises the periosteum cell of claim 1 . 8 . Method for the production of an immortalized periosteum cell, comprising the following steps: 1. providing an isolated periosteum primary cell, and 2. immortalizing the periosteum primary cell for obtaining an immortalized periosteum cell. 9 . The method of claim 8 , wherein the immortalization occurs by transduction of the large T-antigen of the SV40 virus into the periosteum primary cell.
Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof (preparing medicinal viral antigen or antibody compositions, e.g. virus vaccines, A61K39/00) · CPC title
Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth · CPC title
viral genome or elements thereof as genetic vector · CPC title
Immortalised cells · CPC title
Adult fibroblasts · CPC title
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