Microscope-based system and method for image-guided microscopic illumination
US-2024219703-A1 · Jul 4, 2024 · US
US2016344908A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016344908-A1 |
| Application number | US-201615227668-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 3, 2016 |
| Priority date | Mar 7, 2014 |
| Publication date | Nov 24, 2016 |
| Grant date | — |
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A preparation includes an image sensor, a package, and a transparent plate. The image sensor has an imaging area on a front surface. The package is electrically connected to the image sensor. The transparent plate opposes the front surface of the image sensor with a mounting medium interposed therebetween. On the surface of the transparent plate, first and second grooves are formed. The image sensor is disposed between the first and second grooves.
Opening claim text (preview).
What is claimed is: 1 . A preparation comprising: an image sensor having a front surface and a back surface opposite the front surface, the front surface including an imaging area; a package having a front surface and a rear surface and including a plurality of terminals which are electrically connected to the image sensor via a plurality of electrodes, the front surface of the package contacting or opposing the back surface of the image sensor; and a transparent plate disposed so as to oppose the front surface of the image sensor with a mounting medium interposed therebetween, the mounting medium being used for covering at least part of an object, the transparent plate having first and second grooves on a surface which opposes the front surface of the image sensor, wherein at least part of the image sensor is disposed between the first and second grooves, and at least part of each of the plurality of electrodes is positioned within the first groove or the second groove. 2 . The preparation according to claim 1 , wherein: the first and second grooves are parallel with each other; and in a state in which the surface of the transparent plate on which the first and second grooves are formed opposes the front surface of the image sensor, a direction in which the first and second grooves extend and a direction in which the plurality of electrodes are arranged are parallel with each other. 3 . The preparation according to claim 1 , wherein the first and second grooves extend from one end to the other end of the transparent plate. 4 . The preparation according to claim 1 , wherein: the transparent plate also has third and fourth grooves on the surface on which the first and second grooves are formed; and the third and fourth grooves are provided in parallel with each other while being perpendicular to the first and second grooves. 5 . A transparent plate on which an image sensor and a package are mountable in order of the image sensor and the package, the image sensor having a front surface and a back surface opposite the front surface, the front surface including an imaging area, the package having a front surface and a rear surface and including a plurality of terminals which are electrically connected to the image sensor via a plurality of electrodes, the front surface of the package contacting or opposing the back surface of the image sensor, wherein: the transparent plate has first and second grooves on a surface of the transparent plate; and in a state in which the front surface of the image sensor opposes the surface of the transparent plate on which the first and second grooves are formed, at least part of the image sensor is disposed between the first and second grooves with a mounting medium interposed therebetween, the mounting medium being used for covering at least part of an object, and at least part of each of the plurality of electrodes is positioned within the first groove or the second groove. 6 . The transparent plate according to claim 5 , wherein the first and second grooves are parallel with each other, and in a state in which the image sensor is disposed between the first and second grooves, the first and second grooves extend in parallel with a direction in which the plurality of electrodes are arranged. 7 . The transparent plate according to claim 5 , wherein the first and second grooves extend from one end to the other end of the transparent plate. 8 . The transparent plate according to claim 5 , wherein: the transparent plate also has third and fourth grooves on the surface on which the first and second grooves are formed; and the third and fourth grooves are provided in parallel with each other while being perpendicular to the first and second grooves. 9 . A method for producing a preparation, comprising: preparing an image sensor unit including an image sensor and a package, the package including a plurality of terminals which are electrically connected to the image sensor via a plurality of electrodes; disposing an object on a surface of a transparent plate on which first and second grooves are formed or on an imaging area of the image sensor; applying a mounting medium to the object; disposing, before the mounting medium dries, at least part of the image sensor unit between the first and second grooves in a state in which the surface of the transparent plate opposes the imaging area of the image sensor with the mounting medium interposed therebetween, so as to position at least part of each of the plurality of electrodes within the first groove or the second groove; and fixing the image sensor unit and the transparent plate by drying the mounting medium. 10 . An imaging apparatus comprising: a socket on which the preparation according to claim 1 is mountable, the socket being electrically connected to the image sensor via the plurality of terminals of the package of the preparation; a light source unit that emits light to be incident on the image sensor via the transparent plate of the preparation mounted on the socket; and a control device that controls the light source unit and the image sensor of the preparation mounted on the socket so as to cause the image sensor to image the object in the preparation. 11 . The imaging apparatus according to claim 10 , wherein: the light source unit includes a plurality of light sources or a light source which is movable; and the control device performs control so that light will be applied to the object a plurality of times at different angles so as to image the object at each of the different angles. 12 . An imaging method comprising: mounting the preparation according to claim 1 on a socket of an imaging apparatus so as to electrically connect the socket to the image sensor via the plurality of terminals of the package of the preparation; emitting light from a light source unit to be incident on the image sensor via the transparent plate of the preparation; and causing the image sensor to image the object in the preparation mounted on the socket by controlling the light source unit and the image sensor of the preparation. 13 . The imaging method according to claim 12 , wherein: the light source unit includes a plurality of light sources or a light source which is movable; and in the causing of the image sensor to image the object, light is applied to the object a plurality of times at different angles so as to image the object at each of the different angles. 14 . A preparation producing apparatus comprising: a table that supports slide glass on which a specimen section is placed; and a movable unit that fixes an image sensor unit to the slide glass by bringing the image sensor unit close to the slide glass, the image sensor unit including an image sensor and a package, the image sensor having a front surface and a back surface, the package having a front surface and a rear surface, the package supporting the image sensor so that the front surface of the package contacts or opposes the back surface of the image sensor, the package including a plurality of terminals which are electrically connected to the image sensor via a plurality of electrodes, wherein the slide glass is disposed so as to oppose the front surface of the image sensor, the slide glass has first and second grooves on a surface which opposes the front surface of the image sensor, at least part of the image sensor is disposed between the first and second grooves, and at least part of each of the plurality of electrodes is positioned within the first groove or the second groove. 15 . A preparation component s
between a chip and a stacked insulating package substrate, interposer or RDL · CPC title
being orthogonal to a side surface of the chip, e.g. parallel arrangements · CPC title
Optical parts specially adapted for electronic image sensors; Mounting thereof · CPC title
arranged for photographic purposes or projection purposes (G02B21/18 takes precedence){or digital imaging or video purposes including associated control and data processing arrangements (image data processing per se G06T)} · CPC title
Mounting of pick-up tubes, electronic image sensors, deviation or focusing coils · CPC title
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