Oral care compositions and methods

Patent metadata

Field	Value
Publication number	US-2016338938-A1
Application number	US-201315106675-A
Country	US
Kind code	A1
Filing date	Dec 20, 2013
Priority date	Dec 20, 2013
Publication date	Nov 24, 2016
Grant date	—

Abstract

Provided is an oral care composition comprising a phosphate/acrylate co-polymer, zinc and an orally acceptable carrier and methods of using the same.

First claim

1 . An oral care composition comprising a phosphate/acrylate co-polymer, zinc, and an orally acceptable carrier.

2 . The composition of claim 1 wherein the wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1:

wherein n is 0, 1 or 2.

3 . The composition of claim 2 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 70-90%; methacrylic acid in a molar percentage of 5-20%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 1-10%,

4 . The composition of claim 2 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 80-90% or 85%; methacrylic acid in a molar percentage of 5-15% or 11%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 2-6% or 4%.

5 . The composition of claim 1 , wherein the phosphate/acrylate copolymer is a random copolymer having a weight average molecular weight of 10,000 to 500,000, and the phosphate/acrylate copolymer is below it glass transition temperature.

6 . The composition of claim 5 , wherein the weight average molecular weight is 10,000 to 200,000 grams per mole, optionally, 10,000 to 40,000, 15,000 to 25,000, or 17,000 to 23,000 grams per mole.

7 . The composition of claim 1 , wherein the zinc comprises a soluble zinc compound.

8 . The composition of claim 1 , wherein the zinc comprises an insoluble zinc compound.

9 . The composition of claim 1 , wherein the zinc comprises a mixture of soluble and insoluble zinc compounds.

10 . The composition of claim 1 , wherein the zinc composition comprises ZnO.

11 . The composition of claim 1 , wherein the composition comprises 0.1 to 10 weight % ZnO, optionally, 0.1 to 5 weight %, 0.1 to 3 weight %, or 0.1 to 1 weight % ZnO.

12 . The composition of claim 1 , wherein the composition comprises zinc citrate.

13 . The composition of claim 1 , wherein the composition comprises one or more of water, a thickener, a buffer, a humectant, a surfactant, an abrasive, a sweetener, a flavorant, a visual aid (e.g., a pigment, a dye, or a mixture thereof), an anti-caries agent, an anti-bacterial, a whitening agent, a desensitizing agent, a vitamin, a preservative, an enzyme, or a mixture thereof.

14 . The composition of claim 1 , wherein the composition is a mouthwash, toothpaste, tooth gel, tooth powder, non-abrasive gel, mousse, foam, mouth spray, lozenge, oral tablet, dental implement, or pet care product.

15 . The composition of claim 1 , comprising:

Ingredient
%

70% Sorbitol
20

99.0%-101.0% Glycerin
20

Water
Q.S.

High Cleaning Silica
10

Abrasive Silica
8.8

Thickening Silica
2.7

DV8801 Polymer
1-6

Zinc Oxide
0-1

Sodium Lauryl Sulfate
1.5

Sodium Hydroxide
  0-1.2

Sodium CMC - Type 12
1.1

Flavor
1.0-1.2

Titanium Dioxide
0.75

Propylene Glycol
0.5

Carrageenan Gum
0.48

Sodium Saccharin
0.3

Sodium Fluoride
0.243

16 . A method for the treatment and/or inhibition of a chemical stain, plaque, acid erosion, and/or tartar on a dental surface, comprising contacting the dental surface with a composition of any of the foregoing claims.

17 . (canceled)

18 . A method for the treatment and/or inhibition of gum disease comprising contacting the oral cavity with a composition of claim 1 .

19 . (canceled)

20 . A method for the treatment and/or inhibition of halitosis comprising contacting the oral cavity with a composition of claim 1 .

21 . (canceled)

22 . A method for the inhibition of biofilm formation on a dental surface comprising contacting the oral cavity with a composition of claim 1 .

23 . (canceled)

24 . A method for treating and/or inhibiting bacteria from sticking together and growing into bigger colonies in an oral cavity comprising contacting the oral cavity with a composition of claim 1 .

25 . (canceled)

Assignees

• Colgate Palmolive Co

Inventors

• Prencipe Michael
• Jogun Suzanne
• Morgan Andre Michelle
• Chen Xiang

Classifications

• A61K8/8152 Primary

  Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers · CPC title

• A61K8/19

  containing inorganic ingredients · CPC title

• C09D143/02

  Homopolymers or copolymers of monomers containing phosphorus · CPC title

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title