Ceramide Production Enhancer and Moisturizer

Patent metadata

Field	Value
Publication number	US-2016338933-A1
Application number	US-201615229672-A
Country	US
Kind code	A1
Filing date	Aug 5, 2016
Priority date	Oct 5, 2009
Publication date	Nov 24, 2016
Grant date	—

Abstract

A ceramide production enhancer and a moisturizer containing, as an active ingredient, an extract of at least one plant selected from the group consisting of Chenopodium hybridum, Melia toosendan, Indigofera tinctoria, Cirsium japonicum, Catalpa ovata , and Tagetes erecta , or a compound represented by the following Formula (1):

wherein, R represents an acyl group having 1 to 5 carbon atom(s).

First claim

What is claimed is:

1 .- 10 . (canceled)

11 . A method of increasing ceramide in dry human skin, comprising applying a compound represented by the following Formula (1) to the dry skin:

wherein, R represents an acyl group having 1 to 5 carbon atom(s),
and increasing the amount of ceramide in the skin as a result of the applying.

12 . A method of moisturizing dry human skin, comprising applying a compound represented by the following Formula (1) to the dry skin:

wherein, R represents an acyl group having 1 to 5 carbon atom(s),
and moisturizing the skin as a result of the applying.

13 .- 14 . (canceled)

15 . The method of claim 11 , wherein R is an acyl group having 1 to 3 carbon atoms.

16 . The method of claim 12 , wherein R is an acyl group having 1 to 3 carbon atoms.

17 . The method of claim 15 , wherein R is a formyl group, an acetyl group, a propionyl group, a butyryl group, an isobutyryl group, a valeryl group or an isovaleryl group.

18 . The method of claim 16 , wherein R is a formyl group, an acetyl group, a propionyl group, a butyryl group, an isobutyryl group, a valeryl group or an isovaleryl group.

19 . The method of claim 17 , wherein R is a formyl group, an acetyl group or a propionyl group.

20 . The method of claim 18 , wherein R is a formyl group, an acetyl group or a propionyl group.

21 . The method of claim 19 , wherein R is a formyl group.

22 . The method of claim 20 , wherein R is a formyl group.

23 . The method of claim 11 , wherein the compound is applied in the form of an external preparation for skin that comprises the compound.

24 . The method of claim 12 , wherein the compound is applied in the form of an external preparation for skin that comprises the compound.

25 . The method of claim 23 , wherein the compound is applied in a liquid form, solid form, emulsion form, paste form, gel form, powder form, granule form, pellet form, or stick form.

26 . The method of claim 24 , wherein the compound is applied in a liquid form, solid form, emulsion form, paste form, gel form, powder form, granule form, pellet form, or stick form.

27 . The method of claim 25 , wherein the external preparation for skin is a cream, lotion, gel, ointment, paste, pack, sheet-like product.

28 . The method of claim 26 , wherein the external preparation for skin is a cream, lotion, gel, ointment, paste, pack, sheet-like product.

29 . The method of claim 25 , the preparation contain is 0.00001% to 20% by mass of the compound.

30 . The method of claim 26 , the preparation contain is 0.00001% to 20% by mass of the compound.

31 . The method of claim 11 , wherein the subject is an adult and the amount of the compound that is applied is 0.01 mg to 100 mg per day.

32 . The method of claim 12 , wherein the subject is an adult and the amount of the compound that is applied is 0.01 mg to 100 mg per day.

Assignees

• Kao Corp

Inventors

• Shimotoyodome Yoshie
• Ito Shotaro
• Sugai Yoshiya
• Hashimoto Hiroshi
• Ishikawa Junko

Classifications

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61P17/16

  Emollients or protectives, e.g. against radiation · CPC title

• C07D493/08

  Bridged systems · CPC title

• A23P10/30

  Encapsulation of particles, e.g. foodstuff additives · CPC title

• A61K31/58

  containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin (digitoxin {A61K31/7048}) · CPC title