Radiation dosage monitoring system

Patent metadata

Field	Value
Publication number	US-2016332000-A1
Application number	US-201615089494-A
Country	US
Kind code	A1
Filing date	Apr 2, 2016
Priority date	May 12, 2015
Publication date	Nov 17, 2016
Grant date	—

Abstract

Some embodiments are directed to a radiation dosage monitoring system including a model generation module configured to generate a 3D surface model of a portion of a patient undergoing radiation treatment, an image detector configured to detect Cherenkov radiation and any subsequent secondary and scattered radiation originating due to the initial Cherenkov radiation emitted from the patient, a processing module configured to determine estimations of radiation applied to the patient utilizing the images from the image detector and the 3D model, and to utilize the determined estimations of radiation applied to the patient together with data indicative of the orientation of a radiation beam inducing emission of the Cherenkov radiation at a time when the radiation beam was applied to generate a 3D internal representation of the location of the portions of a irradiated patient resulting in the emission of the Cherenkov radiation.

First claim

1 . A radiation dosage monitoring system for determining internal radiation dosages received by a patient undergoing radiation treatment comprising:
a model generation module operable to generate a 3D model of the surface of a portion of a patient undergoing radiation treatment; an image detector operable to detect Cherenkov radiation and any subsequent secondary and scattered radiation originating due to the initial Cherenkov radiation emitted from a surface of the patient undergoing radiation treatment; and a processing module operable to determine estimations of radiation dosages received by internal portions of a patient by:
determining estimations of radiation applied to the surface of a patient utilizing the images obtained by the image detector and the generated 3D model; and
utilizing the determined estimations of radiation applied to the surface of the patient together with data indicative of the orientation of a radiation beam inducing emission of Cherenkov radiation and a model of the absorption of radiation by tissue in a portion of a patient being irradiated to determine estimations of radiation dosages received by internal portions of the patient.

2 . A radiation dosage monitoring system according to claim 1 wherein the data indicative of the orientation of a radiation beam inducing emission of Cherenkov radiation comprises data determined from a radiotherapy treatment plan.

3 . A radiation dosage monitoring system according to claim 1 wherein the image detector is operable to monitor the position and orientation of a treatment apparatus relative to a patient being irradiated and the processing module is operable to determine the orientation of a radiation beam inducing emissions of Cherenkov radiation from the position and orientation of a treatment apparatus relative to a patient being irradiated.

4 . A radiation dosage monitoring system according to claim 1 wherein the processing module is operable to determine estimations of radiation applied to the surface of a patient utilizing the images obtained by the image detector and the generated 3D model of the surface of a portion of a patient undergoing radiation treatment by texture rendering data derived from the obtained images onto the surface of the generated 3D model.

5 . A radiation dosage monitoring system according to claim 4 wherein the image detector comprises a plurality of image detectors and the processing module is operable to determine estimations of radiation applied to the surface of a patient utilizing images obtained by the plurality of image detectors to texture render the generated 3D model of the surface of a portion of a patient undergoing radiation treatment.

6 . A radiation dosage monitoring system according to claim 1 wherein the processing module is operable to process images obtained by the image detector and determine a representation of the location of the portions of a patient irradiated by radiation resulting in the emission of the Cherenkov radiation by:
obtaining a first image of a patient from a view point without radiation being applied to the patient;
obtaining a second image of a patient from the same viewpoint under the same lighting conditions as the first image with radiation being applied to the patient; and
determining a difference image subtracting image values for pixels in the first image from corresponding pixel values in the second image.

7 . A radiation dosage monitoring system according to claim 6 wherein the processing module is operable to process images obtained by the image detector and determine a representation of the location of the portions of a patient irradiated by radiation resulting in the emission of the Cherenkov radiation by determining the sum of pixel values in difference images for corresponding pixels in a set of images a patient from the same viewpoint under the same lighting conditions as the first image with radiation being applied to the patient.

8 . A radiation dosage monitoring system according to claim 7 wherein the processing module is operable to process images in a set of images a patient from the same viewpoint under the same lighting conditions as the first image with radiation being applied to the patient to identify saturated pixels or pixel values corresponding to statistical outliers appearing in images which do not appear in a successive image; wherein such saturated pixel values are not utilized to determine a representation of the location of the portions of a patient irradiated by radiation resulting in the emission of the Cherenkov radiation.

9 . A radiation dosage monitoring system according to claim 7 wherein the set of images comprise images obtained when the surface of a patient is in a defined position and the orientation of a radiation beam inducing emission of Cherenkov radiation is determined to be in the same orientation.

10 . A radiation dosage monitoring system according to claim 9 wherein utilizing the determined estimations of radiation applied to the surface of the patient together with data indicative of the orientation of a radiation beam inducing emission of Cherenkov radiation to determine estimations of radiation dosages received by internal portions of the patient comprises:
texture rendering data derived from the obtained set of images onto the surface of the generated 3D model to determine estimations of radiation applied to the surface of a patient in the defined position with the beam of radiation in the determined orientation; and
determining estimations of radiation dosages received by internal portions of the patient by propagating said determined estimations of radiation applied to the surface of a patient in the defined position on the basis of the orientation of a radiation beam associated with the set and a model of the absorption of radiation by the irradiated portion of the patient.

11 . A radiation dosage monitoring system comprising:
a model generation module operable to generate a 3D model of the surface of a portion of a patient undergoing radiation treatment; an image detector operable to detect Cherenkov radiation and any subsequent secondary and scattered radiation originating due the initial Cherenkov radiation emitted from a surface of the patient undergoing radiation treatment; and a processing module operable to process the images obtained by the image detector and a generated model of the surface of a portion of a patient undergoing radiation treatment and data indicative of chromophores present in a patient's skin to determine a representation of the radiation dosages received by the modelled portion of the surface of the patient undergoing radiation treatment.

12 . A radiation dosage monitoring system according to claim 11 wherein the processing module is operable to process images by:
obtaining a first image of a patient from a viewpoint without radiation being applied to the patient;
obtaining a second image of a patient from the same viewpoint under the same lighting conditions as the first image with radiation being applied to the patient; and
determining a difference image subtracting image values for pixels in the first image from corresponding pixel values in the second image.

13 . A radiation dosage monitoring system according to claim 12 wherein the processing module is operable to process images by determining the sum of pixel values in difference images for corresponding pixels in a set of images of a patient in the same position from the same viewpoint under the same lighting conditions as the first image with radiation being applied to the patient.

14 . A radiation dosage monitoring system accordin

Assignees

• Vision Rt Ltd

Inventors

• Hale Gideon Matthew
• Meir Ivan Daniel
• Pawlicki Todd
• Allen Martin

Classifications

• G06T15/04

  Texture mapping · CPC title

• A61N2005/1085

  characterised by the type of particles applied to the patient · CPC title

• G06T2207/30244

  Camera pose · CPC title

• G06T7/0012

  Biomedical image inspection · CPC title

• G06T2200/04

  involving 3D image data · CPC title