Radiopharmaceutical delivery and tube management system

Patent metadata

Field	Value
Publication number	US-2016331998-A1
Application number	US-201615160549-A
Country	US
Kind code	A1
Filing date	May 20, 2016
Priority date	Jun 7, 2012
Publication date	Nov 17, 2016
Grant date	—

Abstract

A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are described herein. Various other components for delivery systems including tubing management systems, primer caps, diffusion chambers, radiation shields and syringe shields, and other devices and methods are also described.

First claim

1 . A primer cap comprising:
a tube connector comprising:
a nut designed and configured to be grasped by a user;
a first fitting operably connected to the nut; and
a bore extending from the first fitting though the nut, wherein the bore is designed to operably connect to a tube and to allow fluid flow from the tube through the nut; and
a cap comprising:
a handle designed to be grasped by the user; and
a sealing lip disposed on a surface of the cap opposite the handle, wherein the sealing lip is designed to create an airtight seal on the bore of the tube connector and facilitate a reversible connection between the cap and the bore.

2 . The primer cap of claim 1 , further comprising a needle tubing section operably connected to the tube connector and fluidly connected to the bore.

3 . The primer cap of claim 2 , further comprising a needle operably connected to the needle tubing section opposite the tube connector.

4 . The primer cap of claim 2 , wherein the tube connector is physically attached to the needle tubing section by one of soldering and gluing.

5 . The primer cap of claim 1 , further comprising a second fitting extending from the first fitting opposite the first fitting.

6 . The primer cap of claim 1 , further comprising a plug insert extending from a surface of the cap opposite the handle and designed and configured to be inserted into the bore.

7 . A method for creating a wet-wet connection between tubing sections comprising:
introducing a needle tubing section into a blood vessel of a patient, wherein the needle tubing section comprises: a tube connector comprising:
a nut designed and configured to be grasped by a user;
a first fitting operably connected to the nut; and
a bore extending from the first fitting though the nut, wherein the bore is designed to operably connect to a tube and to allow fluid flow from the tube through the nut; and
a cap comprising:
a handle designed to be grasped by the user; and
removing the cap from the tubing connector.

8 . The method of claim 7 , wherein an airtight seal is created by the cap during the step of introducing.

9 . The method of claim 7 , wherein a vacuum is created in the bore drawing blood and other fluids from the subject into the needle tubing section.

10 . The method of claim 7 , further comprising connecting a tubing section to the tube connector.

11 . The method of claim 7 , wherein the needle tubing section further comprises a sealing lip disposed on a surface of the cap opposite the handle, wherein the sealing lip is designed to create an airtight seal on the bore and facilitate a reversible connection between the cap and the bore.

12 . The method of claim 7 , wherein the needle tubing section further comprises a plug insert extending from a surface of the cap opposite the handle and designed and configured to be inserted into the bore.

13 . A method for reducing contamination of a tubing section comprising:
introducing a needle tubing section into a blood vessel of a patient, wherein the needle tubing section comprises:
a diffusion chamber designed and configured to allow a user to monitor diffusion of blood into the needle tubing section;
a first connector at a proximal end of the needle tubing section; and
a second connector at a distal end of the needle tubing section, wherein the second connector is configured to connect to a needle; and
removing the needle tubing section when blood from the patient reaches the first connector.

Assignees

• Bayer Healthcare Llc

Inventors

• Hoffman Raymond C
• Tucker Barry L
• Berry David H
• Uram Martin J
• Uber Iii Arthur E
• Descalzi Douglas

Classifications

• A61N5/1007 Primary

  Arrangements or means for the introduction of sources into the body · CPC title

• A61M5/162

  Needle sets, i.e. connections by puncture between reservoir and tube {; Connections between reservoir and tube (in jet-action syringes A61M5/30; connectors for tubes having sealed ends and a needle for piercing them A61M39/14)} · CPC title

• A61M5/1785

  comprising radioactive shield means (syringe shields or holders for storage of radioactive sources G21F5/018) · CPC title

• A61N2005/1021

  Radioactive fluid · CPC title

• A61M39/20

  Closure caps or plugs for connectors or open ends of tubes · CPC title