Oral care compositions and methods

Patent metadata

Field	Value
Publication number	US-2016331669-A1
Application number	US-201315106507-A
Country	US
Kind code	A1
Filing date	Dec 20, 2013
Priority date	Dec 20, 2013
Publication date	Nov 17, 2016
Grant date	—

Abstract

Provided is an oral care composition comprising a phosphate/acrylate co-polymer, a tin salt, and an orally acceptable carrier, and methods of using the same.

First claim

1 . An oral care composition comprising a phosphate/acrylate co-polymer, a tin salt, and an orally acceptable carrier.

2 . The composition of claim 1 wherein the wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1:

wherein n is 0, 1 or 2.

3 . The composition of claim 2 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 70-90%; methacrylic acid in a molar percentage of 5-20%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 1-10%,

4 . The composition of claim 2 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 80-90% or 85%; methacrylic acid in a molar percentage of 5-15% or 11%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 2-6% or 4%.

5 . The composition of claim 1 , wherein the phosphate/acrylate copolymer is a random copolymer having a weight average molecular weight of 10,000 to 500,000, and the phosphate/acrylate copolymer is below it glass transition temperature.

6 . The composition of claim 5 , wherein the weight average molecular weight is 10,000 to 200,000 grams per mole, optionally, 10,000 to 40,000, 15,000 to 25,000, or 17,000 to 23,000 grams per mole.

7 . The composition of claim 1 wherein the tin salt is selected from stannous chloride, stannous fluoride and mixtures thereof.

8 . The composition of claim 1 , wherein the tin salt comprises SnCl 2 .

9 . The composition of claim 1 , wherein the composition comprises 0.1 to 10 weight % SnCl 2 , optionally 0.1 to 5 weight %, 0.1 to 3 weight %, 0.1 to 1.5 weight %, or 0.5 to 1.2 weight % SnCl 2 .

10 . The composition of claim 1 , wherein the composition comprises one or more of water, a thickener, a buffer, a humectant, a surfactant, an abrasive, a sweetener, a flavorant, a pigment, a dye, an anti-caries agent, an anti-bacterial, a whitening agent, a desensitizing agent, a vitamin, a preservative, an enzyme, or a mixture thereof.

11 . The composition of claim 10 , wherein the anti-bacterial agent is selected from the group consisting of triclosan, cetylpyridinium chloride (CPC), chlorhexidine (CHX), water soluble zinc salts, water insoluble zinc salts, zinc oxide, zinc citrate, or a mixture thereof.

12 . The composition of claim 1 , wherein the composition is a mouthwash, toothpaste, tooth gel, tooth powder, non-abrasive gel, mousse, foam, mouth spray, lozenge, oral tablet, dental implement, or pet care product.

13 . A method for the treatment and/or inhibition of a chemical stain, plaque, acid erosion, and/or tartar on a dental surface, comprising contacting the dental surface with a composition of claim 1 .

14 . A use of any of the compositions of claim 1 for the treatment and/or inhibition of a chemical stain, plaque, acid erosion, and/or tartar on a dental surface comprising contacting the dental surface with the composition.

15 . A method for the treatment and/or inhibition of gum disease comprising contacting the oral cavity with a composition of claim 1 .

16 . A use of any of the compositions of claim 1 for the treatment and/or inhibition of gum disease in an oral cavity comprising contacting the oral cavity with the composition.

17 . A method for the treatment and/or inhibition of halitosis comprising contacting the oral cavity with a composition of claim 1 .

18 . A use of any of the compositions according to claim 1 for the treatment and/or inhibition of halitosis in an oral cavity comprising contacting the oral cavity with the composition.

19 . A method for the inhibition of biofilm formation on a dental surface comprising contacting the oral cavity with a composition of claim 1 .

20 . A use of any of the compositions according to claim 1 for the inhibition of biofilm formation on a dental surface comprising contacting the dental surface with the composition.

21 . A method for treating and/or inhibiting bacteria from sticking together and growing into bigger colonies in an oral cavity comprising contacting the oral cavity with a composition of claim 1 .

22 . A use of any of the compositions according to claim 1 for treating and/or inhibiting bacteria from sticking together and growing into bigger colonies in an oral cavity.

Assignees

• Colgate Palmolive Co

Inventors

• Prencipe Michael
• Jogun Suzanne
• Won Betty

Classifications

• A61P31/04

  Antibacterial agents · CPC title

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

• A61K2800/5922

  At least two compounds being classified in the same subclass of A61K8/18 · CPC title

• A61K8/4926

  having six membered rings · CPC title

• A61K8/58

  containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus · CPC title