Method of treating a patient having pulmonary hypertension by long term NO therapy
US-9522247-B2 · Dec 20, 2016 · US
US2016325068A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016325068-A1 |
| Application number | US-201415109662-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 30, 2014 |
| Priority date | Jan 6, 2014 |
| Publication date | Nov 10, 2016 |
| Grant date | — |
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A system ( 10 ) for measuring subject flow in a respiratory therapy device. The system may include a primary pressure generator ( 12 ) connected to a subject circuit ( 18 ), and a secondary pressure generator ( 30 ) connected to a sensor circuit ( 36 ). The sensor circuit and subject circuit may be in fluid communication such that gas form the sensor circuit is introduced into the subject circuit. A measurement of flow parameters of gas through the sensor circuit may convey information related to flow parameters of gas in the subject circuit. The system may be configured such that contaminates from subject flow in the subject circuit do not flow into the sensor circuit.
Opening claim text (preview).
1 . A system for measuring subject flow in a respiratory therapy device, the system comprising: a primary pressure generator configured to generate a first pressurized flow of breathable gas for delivery to a subject through a subject circuit, the subject circuit including a first flow restriction, the first flow restriction causing a pressure difference to occur between a first side and a second of the first flow restriction if gas is flowing through the subject circuit, the second side being opposite the first side; a secondary pressure generator configured to generate a second pressurized flow of breathable gas for delivery to a sensor circuit, the sensor circuit being in fluid communication with the subject circuit such that gas from the second pressurized flow of breathable gas is introduced into the subject circuit at: a first interface on the first side of the first flow restriction, and a second interface on the second side of the first flow restriction; and a sensor in fluid communication with gas in the sensor circuit, the sensor being configured to generate output signals conveying information related to flow parameters of gas through the first flow restriction in the subject circuit. 2 . The system of claim 1 , wherein the sensor circuit comprises a first conduit ( 38 ) connected to the secondary pressure generator which splits to divide the second pressurized flow into a second conduit and a third conduit, the second conduit having an outlet which fluidly interfaces the subject circuit at the first interface, and the third conduit having an outlet which fluidly interfaces the subject circuit at the second interface. 3 . The system of claim 2 , wherein the sensor circuit additionally includes a fourth conduit in fluid communication with the second pressurized flow of breathable gas, the fourth conduit being in fluid communication with the second conduit at a third interface and the third conduit at a fourth interface, and wherein the sensor is coupled to the fourth conduit to facilitate the fluid communication of the sensor with gas in the sensor circuit, such that the sensor and first flow restriction are connected in parallel with respect to the second conduit and the third conduit of the sensor circuit. 4 . The system of claim 3 , wherein the second conduit additionally comprises a second flow restriction between the split of the first conduit and the third interface, and a third flow restriction between the third interface and the first interface, and the third conduit additionally comprises a fourth flow restriction between the split of the first conduit and fourth interface, and a fifth flow restriction between the fourth interface and the second interface. 5 . The system of claim 1 , further comprising one or more processors configured to execute computer program components, the computer program components comprising: a sensor flow component configured to determine, from the output signals generated by the sensor, flow parameters of the flow of breathable gas passing through the fourth conduit of the sensor circuit; and a subject flow component configured to determine flow parameters of the flow of breathable gas through the first flow restriction of the subject circuit, the determination based on a linear relationship of the flow parameters of the flow of gas through the fourth conduit of the sensor circuit and the flow parameters of the flow of gas through the first flow restriction of the subject circuit. 6 . A method of measuring subject flow in a respiratory therapy device, the method comprising: providing a primary pressure generator configured to generate a first pressurized flow of breathable gas for delivery to a subject through a subject circuit, the subject circuit including a first flow restriction, the first flow restriction causing a pressure difference to occur between a first side and a second side of the first flow restriction if gas is flowing through the subject circuit, the second side being opposite the first side; providing a secondary pressure generator configured to generate a second pressurized flow of breathable gas for delivery to a sensor circuit; fluidly communicating gas from the second pressurized flow of breathable gas into the subject circuit at: a first interface on the first side of the first flow restriction, and a second interface on the second side of the first flow restriction; and providing a sensor in fluid communication with gas in the sensor circuit, the sensor being configured to generate output signals conveying information related to flow parameters of gas through the first flow restriction in the subject circuit. 7 . The method of claim 6 , wherein the sensor circuit comprise a first conduit connected to the secondary pressure generator which splits to divide the second pressurized flow into a second conduit and a third conduit, the second conduit having an outlet which fluidly interfaces the subject circuit at the first interface, and the third conduit having an outlet which fluidly interfaces the subject circuit at the second interface. 8 . The method of claim 6 , wherein the sensor circuit additionally includes a fourth conduit in fluid communication with the second pressurized flow of breathable gas, the fourth conduit being in fluid communication with the second conduit at a third interface and the third conduit at a fourth interface, and wherein the sensor is coupled to the fourth conduit to facilitate the fluid communication of the sensor with gas in the sensor circuit, such that the sensor and first flow restriction are connected in parallel with respect to the second conduit and the third conduit of the sensor circuit. 9 . The method of claim 6 , wherein the second conduit additionally comprises a second flow restriction between the split of the first conduit and the third interface, and a third flow restriction between the third interface and the first interface, and the third conduit additionally comprises a fourth flow restriction between the split of the first conduit and fourth interface, and a fifth flow restriction between the fourth interface and the second interface. 10 . The method of claim 6 , further comprising: performing, on one or more physical processors and storage media storing machine-readable instructions, the operations of: determining, from the output signals generated by the sensor, flow parameters of the flow of breathable gas passing through the fourth conduit of the sensor circuit; and determining flow parameters of the flow of breathable gas through the first flow restriction of the subject circuit, the determination based on a linear relationship of the flow parameters of the flow of gas through the fourth conduit of the sensor circuit and the flow parameters of the flow of gas through the first flow restriction of the subject circuit. 11 . A system for measuring subject flow in a respiratory therapy device, the system comprising: primary flow generating means configured to generate a first pressurized flow of breathable gas for delivery to a subject through a subject circuit, the subject circuit including a first flow restriction, the first flow restriction causing a pressure difference to occur between a first side and a second side of the first flow restriction if gas is flowing through the subject circuit, the second side being opposite the first side; secondary flow generating means configured to generate a second pressurized flow of breathable gas for delivery to a sensor circuit, the sensor circuit being in fluid communication with the subject circuit such that gas from the second pressurized flow of breathable gas is introduced into the subject circuit at: a first interface
Measuring breath flow · CPC title
in the inspiratory circuit · CPC title
Connecting tubes · CPC title
Passive resistors therefor · CPC title
including calculation means, e.g. using a processor · CPC title
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