Thraustochytrids, fatty acid compositions, and methods of making and uses thereof

Patent metadata

Field	Value
Publication number	US-2016309748-A1
Application number	US-201615209568-A
Country	US
Kind code	A1
Filing date	Jul 13, 2016
Priority date	Mar 19, 2009
Publication date	Oct 27, 2016
Grant date	—

Abstract

The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.

First claim

1 .- 10 . (canceled)

11 . An isolated thraustochytrid biomass, wherein at least about 50% by weight of the dry cell weight of the biomass are fatty acids, and wherein at least about 50% by weight of the fatty acids are omega-3 fatty acids.

12 . The isolated thraustochytrid biomass of claim 11 , wherein at least about 50% by weight of the fatty acids is docosahexaenoic acid.

13 . An isolated thraustochytrid biomass, wherein at least about 25% by weight of the dry cell weight of the biomass is docosahexaenoic acid.

14 . The isolated thraustochytrid biomass of any one of claims 10 to 13 , wherein about 10% or less by weight of the fatty acids is eicosapentaenoic acid, and wherein the weight ratio of docosahexaenoic acid to eicosapentaenoic acid is at least about 5:1.

15 . The isolated thraustochytrid biomass of any one of claims 10 to 14 , wherein about 1.5% or less by weight of the fatty acids is arachidonic acid, and wherein the weight ratio of docosahexaenoic acid to arachidonic acid is at least about 20:1.

16 . The isolated thraustochytrid biomass of any one of claims 10 to 15 , further comprising docosahexaenoic acid and docosapentaenoic acid n-6 in a weight ratio of at least about 10:1.

17 - 18 . (canceled)

19 . A food product, cosmetic, or pharmaceutical composition for animals or humans, comprising the thraustochytrid microorganism or thraustochytrid biomass of any one of claims 1 to 9 or mixtures thereof.

20 - 30 . (canceled)

31 . The food product of claim 19 , wherein the food product is an additive for animal or human food.

32 . The food product of claim 19 , wherein the food product is a nutritional supplement.

33 . The food product of claim 19 , wherein the food product is an animal feed.

34 . The animal feed of claim 33 , wherein the animal feed is an aquaculture feed.

35 . The animal feed of claim 33 , wherein the animal feed is a domestic animal feed, a zoological animal feed, a work animal feed, a livestock feed, or a combination thereof.

36 - 50 . (canceled)

51 . The isolated thraustochytrid biomass of any one of the preceding claims, wherein said biomass further comprising at least one antioxidant.

Assignees

• Dsm Ip Assets Bv

Inventors

• Apt Kirk E
• Pfeifer Iii Joseph W
• Hansen Jon Milton
• Behrens Paul Warren
• Zirkle Ross
• Stahl Tracey Lynn

Classifications

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

• A61K8/9728

  Fungi, e.g. yeasts · CPC title

• A23K20/158 Primary

  Fatty acids; Fats; Products containing oils or fats · CPC title

• A61K36/02

  Algae · CPC title

• A61K31/20

  having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids · CPC title