Fibers, composition for producing fibers, and biomaterial containing fibers

Patent metadata

Field	Value
Publication number	US-2016305044-A1
Application number	US-201415106463-A
Country	US
Kind code	A1
Filing date	Dec 19, 2014
Priority date	Dec 20, 2013
Publication date	Oct 20, 2016
Grant date	—

Abstract

The invention provides a fiber which is superior in safety, can be conveniently produced, and has organic solvent resistance, as well as a starting material composition for producing the fiber and a biocompatible material containing the fiber. The fiber is produced by spinning a composition containing (A) a condensation product obtained by condensing one or more kinds of a compound represented by the formula (1), and (B) an acid compound:

wherein each symbol is as defined herein.

First claim

1 . A fiber produced by spinning a composition comprising
(A) a condensation product obtained by condensing one or more kinds of a compound represented by the formula (1), and (B) an acid compound:

wherein
R 1 is an amino group optionally substituted by an alkoxymethyl group having 2-6 carbon atoms or a hydroxymethyl group, an alkyl group having 1-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an aryl group having 6-14 carbon atoms; and
R 2 , R 3 , R 4 and R 5 are the same or different and each is a hydrogen atom, a hydroxymethyl group, an alkoxymethyl group having 2-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an alkyl group having 1-6 carbon atoms.

2 . The fiber according to claim 1 , wherein the above-mentioned composition further comprises (C) a solvent.

3 . The fiber according to claim 1 , wherein the above-mentioned R 1 is selected from an amino group optionally substituted by a methoxymethyl group, an ethoxymethyl group, a propoxymethyl group, a butoxymethyl group or a hydroxymethyl group, a vinyl group, a propenyl group, a butenyl group, a phenyl group and a naphthyl group, and
the above-mentioned R 2 , R 3 , R 4 and R 5 are the same or different and each is selected from a hydrogen atom, a hydroxymethyl group, a methoxymethyl group, an ethoxymethyl group, a propoxymethyl group, a butoxymethyl group, a vinyl group, a propenyl group, a butenyl group, a methyl group, an ethyl group, a propyl group and a butyl group.

4 . The fiber according to claim 1 , wherein
(A) the condensation product is a condensation product obtained by condensing a compound represented by the formula (1A):

wherein
R 1A is an amino group optionally substituted by an alkoxymethyl group having 2-6 carbon atoms or a hydroxymethyl group; and
R 2 , R 3 , R 4 and R 5 are the same or different and each is a hydrogen atom, a hydroxymethyl group, an alkoxymethyl group having 2-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an alkyl group having 1-6 carbon atoms, and/or
a compound represented by the formula (1B):

wherein
R 1B is an aryl group having 6-14 carbon atoms; and
R 2 , R 3 , R 4 and R 5 are the same or different and each is a hydrogen atom, a hydroxymethyl group, an alkoxymethyl group having 2-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an alkyl group having 1-6 carbon atoms.

5 . The fiber according to claim 1 , wherein
(A) the condensation product has a weight average molecular weight of 1,000-1,000,000.

6 . The fiber according to claim 1 , wherein the above-mentioned spinning is electrospinning.

7 . The fiber according to claim 1 , which is a nanofiber and/or a microfiber.

8 . A composition for producing a fiber, comprising
(A) a condensation product obtained by condensing one or more kinds of a compound represented by the formula (1), and (B) an acid compound:

wherein
R 1 is an amino group optionally substituted by an alkoxymethyl group having 2-6 carbon atoms or a hydroxymethyl group, an alkyl group having 1-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an aryl group having 6-14 carbon atoms; and
R 2 , R 3 , R 4 and R 5 are the same or different and each is a hydrogen atom, a hydroxymethyl group, an alkoxymethyl group having 2-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an alkyl group having 1-6 carbon atoms.

9 . The composition according to claim 8 , further comprising (C) a solvent.

10 . The composition according to claim 8 , wherein
(A) the condensation product is a condensation product obtained by condensing a compound represented by the formula (1A):

wherein
R 1A is an amino group optionally substituted by an alkoxymethyl group having 2-6 carbon atoms or a hydroxymethyl group; and
R 2 , R 3 , R 4 and R 5 are the same or different and each is a hydrogen atom, a hydroxymethyl group, an alkoxymethyl group having 2-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an alkyl group having 1-6 carbon atoms, and/or
a compound represented by the formula (1B):

wherein
R 1B is an aryl group having 6-14 carbon atoms; and
R 2 , R 3 , R 4 and R 5 are the same or different and each is a hydrogen atom, a hydroxymethyl group, an alkoxymethyl group having 2-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an alkyl group having 1-6 carbon atoms.

11 . The composition according to claim 8 , wherein
(A) the condensation product has a weight average molecular weight of 1,000-1,000,000.

12 . The composition according to claim 8 , wherein
(A) the condensation product has a solid content of 1-90 wt %.

13 . A production method of a fiber, comprising
(first step) a step of obtaining (A) a condensation product solution by condensing a monomer composition containing one or more kinds of a compound represented by the formula (1), (second step) a step of obtaining a composition for producing a fiber by adding (B) an acid compound and (C) a solvent to the aforementioned (A) the condensation product solution, and (third step) a step of spinning the aforementioned composition for producing a fiber:

wherein
R 1 is an amino group optionally substituted by an alkoxymethyl group having 2-6 carbon atoms or a hydroxymethyl group, an alkyl group having 1-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an aryl group having 6-14 carbon atoms; and
R 2 , R 3 , R 4 and R 5 are the same or different and each is a hydrogen atom, a hydroxymethyl group, an alkoxymethyl group having 2-6 carbon atoms, an alkenyl group having 2-6 carbon atoms or an alkyl group having 1-6 carbon atoms.

14 . The method according to claim 13 , further comprising a step of heating the spun fiber at 50-300° C.

15 . The method according to claim 13 , wherein the above-mentioned spinning is electrospinning.

16 . A biocompatible material comprising the fiber according to claim 1 .

Assignees

• Nissan Chemical Ind Ltd

Inventors

• Kishioka Takahiro
• Umezaki Makiko
• Otani Ayako

Classifications

• D01D5/003

  the material being a polymer solution or dispersion (D01D5/0053 takes precedence) · CPC title

• D01D5/0007

  Electro-spinning (non-woven fabrics produced by electro-spinning D04H1/728) · CPC title

• D01D5/084

  Heating filaments, threads or the like, leaving the spinnerettes · CPC title

• D01F6/76

  from other polycondensation products · CPC title

• D01F6/74 Primary

  from polycondensates of cyclic compounds, e.g. polyimides, polybenzimidazoles · CPC title