Method and system for determining a temporospatially-fractionated radiotherapy planning
US-2024424320-A1 · Dec 26, 2024 · US
US2016303398A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016303398-A1 |
| Application number | US-201315106097-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 20, 2013 |
| Priority date | Dec 20, 2013 |
| Publication date | Oct 20, 2016 |
| Grant date | — |
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A method for generating a radiotherapy treatment plan for a patient is provided. The treatment plan is optimized using an optimization objective which is at least partly based on an initially planned dose to the patient.
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1 : A method for generating a radiotherapy treatment plan for a patient by optimizing treatment parameters on the basis of one or more optimization objectives, said method comprising, in a processor: obtaining an initial treatment plan comprising an initial dose distribution; modifying the initial dose distribution for at least one region of the patient to obtain a modified dose distribution; and optimizing an objective function using the modified dose distribution as an optimization objective included in the objective function. 2 : The method according to claim 1 , wherein said initial radiotherapy treatment planning result comprises initially planned treatment parameters which are utilized as a starting point for generating the radiotherapy treatment plan. 3 : The method according to claim 1 , wherein one or more of said optimization objectives is at least partly based on a spatial dose distribution corresponding to said initially planned dose. 4 : The method according to claim 1 , wherein one or more of said optimization objectives is at least partly based on a dose volume histogram corresponding to said initially planned dose. 5 : The method according to claim 1 , wherein one or more of said optimization objectives is at least partly based on a characteristic dose fall-off corresponding to said initially planned dose. 6 : The method according to claim 1 , wherein one or more of said optimization objectives is an additional objective not based on said initially planned dose. 7 - 8 . (canceled) 9 : A computer program product comprising computer-readable instructions which, when executed on a computer, causes the computer to perform a method according to claim 1 . 10 : The computer program product according to claim 9 , configured for receiving user-input regarding an additional objective and/or a modification of said initially planned dose and defining one or more of said optimization objectives on the basis of said user-input. 11 : A computer system comprising a processor coupled to at least one memory having stored thereon a computer program comprising computer-readable instructions, said processor configured to, by executing said computer-readable instructions, perform a method according to claim 1 . 12 : The computer system according to claim 11 , wherein the system further comprises a data input device enabling a user to input data regarding an additional objective and/or a modification of said initially planned dose. 13 : The method according to claim 1 , wherein a user interactively applies one or more modifications to the initially planned dose distribution while monitoring the optimized dose distribution until a satisfactory result has been obtained. 14 : The method according to claim 13 , wherein the initial dose distribution is replaced with the current optimized dose distribution. 15 : The method according to claim 1 , wherein the optimization of treatment parameters involves optimizing machine parameters. 16 : The method according to claim 1 , wherein user-input regarding an additional objective and/or a modification of said initially planned dose is received from a user via a user-input interface and utilized for defining one or more of said optimization objectives.
using a specific method of dose optimization · CPC title
Simulated annealing · CPC title
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