Microfluidic devices and systems, and methods for operating microfluidic devices and systems
US-2024408596-A1 · Dec 12, 2024 · US
Enhanced Aerosol Test For Assessing Filter Integrity
US2016299048A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016299048-A1 |
| Application number | US-201615057641-A |
| Country | US |
| Kind code | A1 |
| Filing date | Mar 1, 2016 |
| Priority date | Apr 8, 2015 |
| Publication date | Oct 13, 2016 |
| Grant date | — |
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- Title
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Abstract
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A method of aerosol integrity testing of filters, capable of detecting single defects that are less than 20 μm in diameter, and even as small as 2 μm in diameter, in liquid sterilizing grade filters such as filter cartridges. The method challenges the filter in a dry state with a particle stream of aerosol particles of the appropriate size and in the appropriate concentration, such that at least one or more of the particles in the stream will penetrate a defective region or regions within the membrane but will not penetrate in the integral region of the membrane. Wetting of the filter is not required.
First claim
Opening claim text (preview).
What is claimed is: 1 . A method of integrity testing a filter in the dry state, comprising: providing a liquid sterilizing grade filter to be tested in a dry state; generating an aerosol particle stream wherein the particles in said stream have a suitable size and a suitable concentration to challenge said filter and penetrate any defective region in said filter but will not penetrate integral regions in said filter; and detecting particles that penetrate said defective region. 2 . The method of claim 1 , wherein particles that penetrate defects in said filter that are as small as 2 microns are detected. 3 . The method of claim 1 , wherein said filter is pleated. 4 . The method of claim 1 , wherein said filter is housed in a cartridge. 5 . The method of claim 1 , wherein said aerosol particle stream comprises NaCl.
Assignees
Inventors
Classifications
- G01N15/0806Primary
Details, e.g. sample holders, mounting samples for testing · CPC title
Testing filters · CPC title
and measuring fluid flow rate, i.e. permeation rate or pressure change · CPC title
- G01N15/088Primary
Investigating volume, surface area, size or distribution of pores; Porosimetry · CPC title
Testing of filters, filter elements, sealings · CPC title
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- What does patent US2016299048A1 cover?
- A method of aerosol integrity testing of filters, capable of detecting single defects that are less than 20 μm in diameter, and even as small as 2 μm in diameter, in liquid sterilizing grade filters such as filter cartridges. The method challenges the filter in a dry state with a particle stream of aerosol particles of the appropriate size and in the appropriate concentration, such that at leas…
- Who is the assignee on this patent?
- Emd Millipore Corp
- What technology area does this patent fall under?
- Primary CPC classification G01N15/0806. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Thu Oct 13 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).