Drug delivery device with dose delivery clicker

Patent metadata

Field	Value
Publication number	US-2016287802-A1
Application number	US-201415036522-A
Country	US
Kind code	A1
Filing date	Nov 17, 2014
Priority date	Apr 24, 2011
Publication date	Oct 6, 2016
Grant date	—

Abstract

A drug delivery device comprises a lead screw having a longitudinal axis, a distal end and a proximal end that is axially movable in a distal direction relative to a mid-body, the lead screw including a threaded shaft, wherein the lead screw has a keyway positioned parallel to the longitudinal axis and containing a first section of a dose dispensing feedback component; the mid-body being designed to prevent rotation of the lead screw with respect to the mid-body, where the mid-body contains a second section of the dose dispensing feedback component.

First claim

1 - 15 . (canceled)

16 . A drug delivery device comprising
a lead screw having a longitudinal axis, a distal end and a proximal end that is axially movable in a distal direction relative to a mid-body, the lead screw including a threaded shaft, wherein the lead screw has a keyway positioned parallel to the longitudinal axis and containing a first section of a dose dispensing feedback component; the mid-body being designed to prevent rotation of the lead screw with respect to the mid-body, where the mid-body contains a second section of the dose dispensing feedback component.

17 . The drug delivery device of claim 16 , where the mid-body includes tabs ( 31 ) that slidably fit within the keyway to prevent the rotation of the lead screw.

18 . The drug delivery device of claim 16 , where the first section of the dose dispensing feedback component comprises a linear arrangement of ratchet teeth.

19 . The drug delivery device of claim 18 , where the second section of the dose dispensing feedback component comprises a spring arm biased inwardly and configured to flex outwardly as the spring arm engages each tooth of the first section of the dose dispensing feedback component as the lead screw is advanced distally through the mid-body.

20 . The drug delivery device of claim 19 , where the engagement of the teeth and the spring arm produces an audible signal.

21 . The drug delivery device of claim 16 , where the engagement of the teeth and the spring arm produces a tactile signal.

22 . The drug delivery device of claim 16 , where the lead screw has at least two keyways each containing a portion of the first section of the dose dispensing feedback component, both portions comprising a linear arrangement of ratchet teeth.

23 . The drug delivery device of claim 22 , where the ratchet teeth of one keyway and the ratchet teeth of another keyway are axially offset.

24 . The drug delivery device of claim 22 , where the pitch of one portion of the linear arrangement of ratchet teeth has a first pitch and the other portion has a second pitch; the first pitch being different than the second pitch, or the first and second pitches being the same.

25 . The drug delivery device of claim 19 , where the spring arm and the ratchet teeth are configured to prevent the lead screw from moving in the proximal direction.

26 . The drug delivery device of claim 16 , where the lead screw has at least two keyways, one containing the dose dispensing feedback component which comprises a linear arrangement of ratchet teeth; the other one containing means which prevents the lead screw from moving in the proximal direction.

27 . The drug delivery device of claim 16 , further comprising a housing; the mid-body being fixed inside the housing in such a manner that rotation of the lead-screw within the housing is prevented.

28 . The drug delivery device of claim 16 ,
wherein a drive nut is threadedly engaged and screwable along the lead screw threaded shaft, wherein a number sleeve is threadedly engaged with the housing to be screwable relative to the housing, wherein a dial link is connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, the dial link being rotatably fixed with the number sleeve when the dial link and the number sleeve are in a first axial arrangement, the number sleeve being rotatable relative to the dial link when the dial link and the number sleeve are in a second axial arrangement.

29 . The drug delivery device of claim 28 wherein an inner sleeve is threadedly engaged with the number sleeve, the inner sleeve being axially movable and rotatably fixed relative to the housing and wherein the inner sleeve is axially movable and rotatably fixed relative to the mid-body.

30 . The drug delivery device of claim 28 wherein during dose setting, the dial link and the number sleeve are in the first axial arrangement, whereby a screwing motion of the dial link and the number sleeve relative to the housing screws the dial link and the number sleeve a first axial distance from a home position, which screwing motion of the dial link screws said drive nut along the lead screw threaded shaft a second axial distance that is different than the first axial distance;
wherein during dose delivery, the dial link and the number sleeve are in said second axial arrangement, whereby a screwing motion of the number sleeve relative to the housing back toward the home position advances the inner sleeve without rotation in the distal direction to axially advance the drive nut that is axially fixed to the inner sleeve and thereby the lead screw and the movable piston to dispense fluid from the cartridge outlet.

Assignees

• Sanofi Aventis Deutschland

Inventors

• Blancke Stefan
• Teucher Axel
• Jugl Michael
• Schneider Christiane

Classifications

• A61M5/31551 Primary

  including axial movement of dose setting member · CPC title

• A61M5/31575

  using scaling up or down transmissions, e.g. gearbox · CPC title

• A61M5/3157

  Means providing feedback signals when administration is completed (A61M5/20 takes precedence) · CPC title

• A61M2205/581

  by audible feedback · CPC title

• A61M2205/582

  by tactile feedback · CPC title