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Compositions and methods for identification of relapse risk and treatment in patients with colorectal cancer
US2016258024A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016258024-A1 |
| Application number | US-201415027284-A |
| Country | US |
| Kind code | A1 |
| Filing date | Oct 7, 2014 |
| Priority date | Oct 7, 2013 |
| Publication date | Sep 8, 2016 |
| Grant date | — |
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Abstract
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In certain aspects, the disclosure relates to methods of predicting recurrence of colorectal cancer by using a combination of microRNAs in the circulation, wherein the microRNAs are selected from the group consisting of miR-15a, miR-103, miR-148a, miR-320a, miR-451 and miR-596. In other aspects, the disclosure relates to methods of treating colorectal cancer by administering a therapeutic agent after determining an increased risk of recurrence.
First claim
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We claim: 1 . A method for predicting recurrence of early stage colorectal cancer in a patient, comprising: a) providing a biological material comprising circulating microRNAs from a patient diagnosed with stage 0, stage I or stage II colorectal cancer, b) measuring in the biological material the levels of two or more microRNAs selected from: miR-15a, miR-103, miR-148a, miR-320a, miR-451 and miR-596, and c) evaluating the measured levels; wherein the measured level…
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- C12Q1/6886Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US2016258024A1 cover?
- In certain aspects, the disclosure relates to methods of predicting recurrence of colorectal cancer by using a combination of microRNAs in the circulation, wherein the microRNAs are selected from the group consisting of miR-15a, miR-103, miR-148a, miR-320a, miR-451 and miR-596. In other aspects, the disclosure relates to methods of treating colorectal cancer by administering a therapeutic agent…
- Who is the assignee on this patent?
- Univ Georgetown
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6886. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu Sep 08 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).