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Methodologies and Reagents for Detecting Fibrinolysis and Hyperfibrinolysis
US2016252534A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016252534-A1 |
| Application number | US-201615149868-A |
| Country | US |
| Kind code | A1 |
| Filing date | May 9, 2016 |
| Priority date | May 5, 2014 |
| Publication date | Sep 1, 2016 |
| Grant date | — |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
In some embodiments, the invention provides a container adapted for detecting hyperfibrinolysis or fibrinolysis in a blood sample using viscoelastic analysis comprising an interior having a coating comprises an inhibitor of fibrinolysis.
First claim
Opening claim text (preview).
What is claimed is: 1 . A container adapted for detecting hyperfibrinolysis or fibrinolysis in a blood sample using viscoelastic analysis comprising an interior having a coating comprises an inhibitor of fibrinolysis. 2 . The container of claim 1 , wherein the inhibitor of fibrinolysis is tranexamic acid. 3 . The container of claim 1 , wherein the inhibitor of fibrinolysis is selected from the group consisting of an aminocaproic acid (ε-aminocaproic acid), and aprotinin. 4 . The container of claim 1 , wherein the viscoelastic analysis is performed using a TEG thromboelastography analyzer system or in a ROTEM thromboelastometry analyzer system. 5 . The container of claim 1 , wherein the inhibitor of fibrinolysis is formulated with sugar in the coating. 6 . The container of claim 1 , wherein the inhibitor is formulated with sodium azide in the coating. 7 . The container of claim 1 , wherein the coating further comprises an inhibitor of platelet function. 8 . The container of claim 7 , wherein the inhibitor of platelet function is a glycoprotein IIb/IIIa receptor inhibitor. 9 . The container of claim 8 , wherein the glycoprotein IIb/IIIa receptor inhibitor is selected from the group consisting of abciximab, eptifibatide, and tirofiban. 10 . The container of claim 7 , wherein the inhibitor of platelet function is an adenosine diphosphate (ADP) receptor inhibitor, adenosine reuptake inhibitor, or a thromboxane inhibitor. 11 . The container of claim 7 , wherein the inhibitor of platelet function is cytochalasin D. 12 . The container of claim 1 , wherein the container is located on a cassette, wherein the cassette further comprises a second container.
Assignees
Inventors
Classifications
- G01N33/86Primary
involving blood coagulating time {or factors, or their receptors} · CPC title
Blood {(chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80)} · CPC title
involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen · CPC title
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Frequently asked questions
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- What does patent US2016252534A1 cover?
- In some embodiments, the invention provides a container adapted for detecting hyperfibrinolysis or fibrinolysis in a blood sample using viscoelastic analysis comprising an interior having a coating comprises an inhibitor of fibrinolysis.
- Who is the assignee on this patent?
- Haemonetics Corp, Univ Colorado Regents
- What technology area does this patent fall under?
- Primary CPC classification G01N33/86. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Thu Sep 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).