Lipid compositions

Patent metadata

Field	Value
Publication number	US-2016228462-A1
Application number	US-201615040347-A
Country	US
Kind code	A1
Filing date	Feb 10, 2016
Priority date	Feb 11, 2015
Publication date	Aug 11, 2016
Grant date	—

Abstract

The present invention provides improved processes for extracting and preparing lipids from biological sources for use in pharmaceuticals, nutraceuticals and functional foods.

First claim

1 . A desalted krill lipid composition comprising:
from about 30% to 50% w/w phospholipids w/w; from about 32% to 52% w/w triglycerides;
and wherein the composition has one or more of the following properties:
a) the composition comprises from about 3% w/w to 13% w/w free fatty acids;
b) the composition comprises from about 0.5% w/w to 5% w/w lysophospholipids;
c) the composition comprises less than about 0.2% w/w inorganic salts;
d) the composition comprises less than about 2 mg N/100 g;
e) the composition comprises less than about 2 ppm Cu ++ ;
f) the composition comprises less than about 3 ppm total arsenic;
g) the composition comprises from about 0.01% to about 1% w/w ethyl esters;
h) the composition is characterized in having a conductivity of less than about 20 μS/cm when measured with 5% dry matter in 95% ethanol;
i) the composition is characterized in having a viscosity of from about 100 to 400 mPas at 25° C.; and
j) the composition comprises from about 20 ppm to about 2000 astaxanthin esters.

2 . The composition of claim 1 , having 2 or more of properties (a) to (j).

3 . The composition of claim 2 , having 3 or more of properties (a) to (j).

4 . The composition of claim 3 , having 4 or more of properties (a) to (j).

5 . The composition of claim 4 , having 5 or more of properties (a) to (j).

6 . The composition of claim 5 , having 6 or more of properties (a) to (j).

7 . The composition of claim 6 , having 7 or more of properties (a) to (j).

8 . The composition of claim 7 , having 8 or more of properties (a) to (j).

9 . The composition of claim 8 , having 9 or more of properties (a) to (j).

10 . The composition of claim 9 , having all of properties (a) to (j).

11 . The composition of claim 1 , having at least properties (c) and (i).

12 . The composition of claim 11 , having at least property (h).

13 . The composition of claim 12 , having at least properties (e) and (f).

14 . The composition of claim 13 , having at least property (d).

15 . The composition of claim 1 , having at least properties (c), (d), (e), (f), (h) and (i).

16 . A krill phospholipid concentrate comprising:
from about 50% to 85% w/w phospholipids; from about 5% to 35% w/w triglycerides;
and wherein the composition has one or more of the following properties:
(a) the composition comprises from about 2% w/w to 13% w/w free fatty acids;
(b) the composition comprises from about 0.5% w/w to 10% w/w lysophospholipids;
(c) the composition comprises less than about 0.2% w/w inorganic salts;
(d) the composition comprises less than about 2 mg N/100 g;
(e) the composition comprises less than about 2 ppm Cu ++ ;
(f) the composition comprises less than about 3 ppm total arsenic;
(g) the composition comprises from about 0.01% to about 1% w/w ethyl esters;
(h) the composition is characterized in having a conductivity of less than about 20 μS/cm when measured with 5% dry matter in 95% ethanol;
(i) the composition is characterized in having a viscosity of from about 600 to 1600 mPas at 35° C.; and
(j) the composition has comprises less than about 100 ppm astaxanthin esters.

17 . The composition of claim 16 , having 2 or more of properties (a) to (j).

18 . The composition of claim 17 , having 3 or more of properties (a) to (j).

19 . The composition of claim 18 , having 4 or more of properties (a) to (j).

20 . The composition of claim 19 , having 5 or more of properties (a) to (j).

21 . The composition of claim 20 , having 6 or more of properties (a) to (j).

22 . The composition of claim 21 , having 7 or more of properties (a) to (j).

23 . The composition of claim 22 , having 8 or more of properties (a) to (j).

24 . The composition of claim 23 , having 9 or more of properties (a) to (j).

25 . The composition of claim 24 , having all of properties (a) to (j).

26 . The composition of claim 16 , having at least properties (c) and (i).

27 . The composition of claim 26 , having at least property (h).

28 . The composition of claim 27 , having at least properties (e) and (f).

29 . The composition of claim 28 , having at least property (d).

30 . The composition of claim 16 , having at least properties (c), (d), (e), (f), (h) and (i).

31 . A krill lipid composition comprising:
from about 30% to 50% w/w phospholipids w/w; from about 26% to 46% w/w triglycerides;
and wherein the composition has one or more of the following properties:
(a) the composition comprises from about 1% w/w to 7% w/w diglycerides;
(b) the composition comprises from about 2% w/w to 12% w/w free fatty acids;
(c) the composition comprises from about 1% w/w to 7% w/w cholesterol;
(d) the composition comprises from about 0.1% w/w to 2% w/w cholesterol esters, more preferably from about 0.2% w/w to about 1.0% w/w cholesterol esters;
(e) the composition comprises from about 0.5% w/w to 5% w/w inorganic salts;
(f) the composition comprises from about 0.5% w/w to 5% w/w tertiary amines.

32 . An oral delivery vehicle comprising the composition of claim 1 .

Assignees

• Aker Biomarine Antarctic As

Inventors

• Myhren Finn
• Hoem Nils
• Saebo Asgeir
• Oroskar Anil R
• Oroskar Asha A
• Mallia Anantha Krishna

Classifications

• C11B1/10

  by extracting · CPC title

• C11B3/006 Primary

  by extraction · CPC title

• A61K31/683

  Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols · CPC title

• A23K20/26

  Compounds containing phosphorus · CPC title

• A61K31/215

  of carboxylic acids · CPC title