One-component-type dentinal tubule sealant

Patent metadata

Field	Value
Publication number	US-2016228336-A1
Application number	US-201415024530-A
Country	US
Kind code	A1
Filing date	Sep 29, 2014
Priority date	Sep 30, 2013
Publication date	Aug 11, 2016
Grant date	—

Abstract

A dentinal tubule sealant including apatite particles (A) having an average particle diameter of 500 nm or less, a filler (B) having an average particle diameter of 1 to 10 μm, and a dispersant (C), wherein the weight ratio (A/B) of the apatite particles (A) to the filler (B) is 0.05 to 15, the dentinal tubule sealant contains 15 to 95 parts by weight of the dispersant (C) relative to 100 parts by weight in total of the apatite particles (A) and the filler (B), and the total amount of the apatite particles (A), the filler (B), and the dispersant (C) is 85 parts by weight or more relative to 100 parts by weight of the dentinal tubule sealant. There is thereby provided a dentinal tubule sealant excelling in dentinal tubule sealability immediately after treatment, durability of dentinal tubule sealing, ease of operation, and storage stability.

First claim

1 : A dentinal tubule sealant, comprising:
(A) apatite particles (A) having an average particle diameter of 500 nm or less; (B) a filler (B) having an average particle diameter of 1 to 10 μm; and (C) a dispersant (C),
wherein:
a weight ratio (A/B) of the apatite particles (A) to the filler (B) is 0.05 to 15;
the dentinal tubule sealant comprises 15 to 95 parts by weight of the dispersant (C) relative to 100 parts by weight in total of the apatite particles (A) and the filler (B); and
a total amount of the apatite particles (A), the filler (B), and the dispersant (C) is 85 parts by weight or more relative to 100 parts by weight of the dentinal tubule sealant.

2 : The dentinal tubule sealant according to claim 1 , wherein the filler (B) is an inorganic filler (b), an organic filler (b′), or both.

3 : The dentinal tubule sealant according to claim 1 , wherein the filler (B) is at least one inorganic filler (b) selected from the group consisting of basic calcium phosphate particles (b1), poorly-soluble calcium phosphate particles (b2), a phosphorus-free calcium compound (b3), and an inorganic filler (b4) other than (b1) to (b3).

4 : The dentinal tubule sealant according to claim 1 , wherein the filler (B) is an inorganic filler (b) selected from the group consisting of a mixture of basic calcium phosphate particles (b1) and poorly-soluble calcium phosphate particles (b2) and a mixture of poorly-soluble calcium phosphate particles (b2) and a phosphorus-free calcium compound (b3), such that a Ca/P ratio of the sum of (b1) and (b2) or the sum of (b2) and (b3) is 1.2 to 2.0.

5 : The dentinal tubule sealant according to claim 1 , wherein the filler (B) is an inorganic filler (b) comprising a mixture of basic calcium phosphate particles (b1), poorly-soluble calcium phosphate particles (b2) and a phosphorus-free calcium compound (b3), such that a Ca/P ratio of the sum of (b1), (b2) and (b3) is 1.5 to 3.0.

6 : The dentinal tubule sealant according to claim 4 , wherein the inorganic filler (b) further comprises an inorganic filler (b4) other than (b1) to (b3).

7 : The dentinal tubule sealant according to claim 1 , wherein the dispersant (C) is water, a nonaqueous liquid, or both.

8 : The dentinal tubule sealant according to claim 7 , wherein the dispersant (C) comprises at least one nonaqueous liquid selected from the group consisting of a polyether, a monohydric alcohol, and a polyhydric alcohol.

Assignees

• Kuraray Noritake Dental Inc

Inventors

• Ishihara Shumei
• Hatanaka Kenji

Classifications

• C04B28/34

  containing cold phosphate binders · CPC title

• C04B2111/00836

  for medical or dental applications · CPC title

• A61K6/17

  Particle size · CPC title

• A61K6/80

  Preparations for artificial teeth, for filling teeth or for capping teeth · CPC title

• A61K6/20

  Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish · CPC title