Biodegradable plant wound dressing composed of electrospun nanofibers

Patent metadata

Field	Value
Publication number	US-2016219874-A1
Application number	US-201614997698-A
Country	US
Kind code	A1
Filing date	Jan 18, 2016
Priority date	Jan 29, 2015
Publication date	Aug 4, 2016
Grant date	—

Abstract

A plant wound dressing composed of a blend of polymers and methods for their manufacture and use are described.

First claim

What is claimed is:

1 . A biodegradable plant wound dressing comprising a plurality of electrospun nanofibers produced from a blend of at least two different polymers, wherein at least one of the polymers is a biopolymer and said dressing is microorganism impermeable.

2 . The biodegradable plant wound dressing of claim 1 , wherein the biopolymer comprises a starch, cellulose, hemicellulose, lignin, pullulan, alginate, chitin, chitosan, dextran, or protein.

3 . The biodegradable plant wound dressing of claim 1 , wherein the biopolymer is derived from biowaste or a by-product.

4 . The biodegradable plant wound dressing of claim 1 , wherein the other polymer comprises a synthetic polymer.

5 . The biodegradable plant wound dressing of claim 4 , wherein the synthetic polymer comprises a polyvinyl alcohol, polycaprolactone, polyesteramide, modified polyethylene terephthalate, polylactic acid, polyglycolic acid, polyalkylene carbonate, polyhydroxyalkanoate, poly-3-hydroxybutyrate, poly-3-hydroxyvalerate, poly-3-hydroxybutyrate-co-4-hydroybutyrate, poly-3-hydroxybutyrate-co-3-hydroxyvalerate copolymer, poly-3-hydroxybutyrate-co-3-hydroxyhexanoate, poly-3-hydroxybutyrate-co-3-hydroxyoctanoate, poly-3-hydroxybutyrate-co-3-hydroxy decanoate, poly-3-hydroxybutyrate-co-3-hydroxyoctadecanoate, polybutylene succinate, polybutylene succinate adipate, an aliphatic-aromatic copolyester, polyethylene succinate or a combination thereof.

6 . The biodegradable plant wound dressing of claim 1 , further comprising at least one adhesive.

7 . The biodegradable plant wound dressing of claim 6 , wherein the at least one adhesive is water soluble.

8 . The biodegradable plant wound dressing of claim 6 , wherein the adhesive is electrospun with the blend of at least two different polymers.

9 . The biodegradable plant wound dressing of claim 6 , wherein the adhesive is electrosprayed onto the electrospun nanofibers.

10 . The biodegradable plant wound dressing of claim 6 , wherein the wound dressing is characterized as having
(a) a peel force of between 0.0005 N and 0.1500 N; (b) a normal specific adhesive energy of between 0.01 N/m and 50 N/m; (c) a shear adhesive specific energy of between 1 N/m and 500 N/m; or (d) a combination of any one of (a), (b) and (c).

11 . The biodegradable plant wound dressing of claim 1 , further comprising a base membrane.

12 . The biodegradable plant wound dressing of claim 11 , wherein the base membrane is biodegradable.

13 . The biodegradable plant wound dressing of claim 12 , wherein the base membrane comprises rayon.

14 . The biodegradable plant wound dressing of claim 1 , wherein the dressing comprises pores of less than about 6 microns.

15 . A method for producing the biodegradable plant wound dressing of claim 1 , comprising blending at least two different polymers, wherein at least one of the polymers is a biopolymer, and electrospinning the blend to produce a biodegradable plant wound dressing.

16 . The method of claim 15 , further comprising electrospinning an adhesive in combination with the blend of at least two different polymers.

17 . The method of claim 15 , wherein the at least two different polymers are electrosprayed onto a base membrane prior to electrospinning.

18 . The method of claim 15 , further comprising electrospraying an adhesive onto the electrospun polymers.

19 . A method for preventing microbial infection of a plant wound comprising applying the biodegradable plant wound dressing of claim 1 to a plant wound thereby preventing microbial infection of a plant wound.

20 . The method of claim 19 , wherein the microbial infection causes vine decline, fungal canker, bacterial canker, blight, or rot.

21 . The method of claim 19 , wherein the biodegradable plant wound dressing, after being applied to the plant wound, stays intact for at least six weeks.

Assignees

• Univ Illinois

Inventors

• Yarin Alexander L
• Sett Soumyadip
• Lee Minwook
• Sinha-Ray Suman

Classifications

• D01D5/003

  the material being a polymer solution or dispersion (D01D5/0053 takes precedence) · CPC title

• A01G1/001

  Human Necessities · mapped topic

• A01N25/24

  containing ingredients to enhance the sticking of the active ingredients · CPC title

• A01G7/06

  Treatment of growing trees or plants, e.g. for preventing decay of wood, for tingeing flowers or wood, for prolonging the life of plants · CPC title

• A01N31/02

  Acyclic compounds · CPC title