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Benzodiazepine dimers, conjugates thereof, and methods of making and using
US2016200742A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016200742-A1 |
| Application number | US-201614994296-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jan 13, 2016 |
| Priority date | Jan 14, 2015 |
| Publication date | Jul 14, 2016 |
| Grant date | — |
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Abstract
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Benzodiazepine dimers having a structure represented by wherein R 1 is wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).
First claim
Opening claim text (preview).
What is claimed is: 1 . A benzodiazepine dimer having a structure represented by formula (I) wherein R 1 is according to formula (Ia) or formula (Ib): each G and G′ is C or N, with the proviso that no more than two Gs or two G's are N; each R…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
- C07D519/00Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US2016200742A1 cover?
- Benzodiazepine dimers having a structure represented by wherein R 1 is wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especi…
- Who is the assignee on this patent?
- Bristol Myers Squibb Co
- What technology area does this patent fall under?
- Primary CPC classification C07D519/00. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu Jul 14 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).