Antiseptic compositions and methods

Patent metadata

Field	Value
Publication number	US-2016184346-A1
Application number	US-201615062493-A
Country	US
Kind code	A1
Filing date	Mar 7, 2016
Priority date	Jan 16, 2002
Publication date	Jun 30, 2016
Grant date	—

Abstract

A skin antisepsis composition comprising a vehicle comprising a (C1-4)alcohol and water in a ratio of at least 60:40, a hydroxycarboxylic acid, a cationic film-forming polymer, and at least one antimicrobial agent; and methods of using the composition are provided.

First claim

1 . An antiseptic composition for use in disinfecting tissue, wherein the antiseptic composition comprises:
an antimicrobial agent selected from the group consisting of iodine, an iodophor, and a combination thereof, wherein the antimicrobial agent is present in an amount sufficient to provide an available iodine concentration of at least 0.25 wt-%; a hydroxycarboxylic acid buffer in a molar concentration of at least 0.3 molar; and water.

2 . The antiseptic composition for use according to claim 1 , wherein the antiseptic composition further includes one or more nonionic, anionic, or amphoteric surfactants.

3 . The antiseptic composition for use according to claim 2 , wherein the surfactant is an anionic or amphoteric surfactant.

4 . The antiseptic composition for use according to claim 3 , wherein the anionic or amphoteric surfactant is selected from the group consisting of sulfonates, sulfates, phosphates, phosphonates, and ammonium sulfonate amphoterics, and mixtures thereof.

5 . The antiseptic composition for use according to claim 4 , wherein the hydroxycarboxylic acid buffer is present in a molar concentration of at least 0.45 molar.

6 . The antiseptic composition for use according to claim 1 , wherein the antiseptic composition further includes a film-forming polymer.

7 . The antiseptic composition for use according to claim 6 , wherein the film-forming polymer is cationic.

8 . The antiseptic composition for use according to claim 1 wherein the iodophor is povidone-iodine.

9 . The antiseptic composition for use according to claim 1 wherein the tissue is skin or mucosal tissue.

10 . The antiseptic composition for use according to claim 9 , wherein the mucosal tissue is nasal or vaginal tissue.

11 . The antiseptic composition for use according to claim 10 , wherein the mucosal tissue is nasal tissue.

12 . The antiseptic composition for use according to claim 1 , wherein the antiseptic composition is to be directly applied to the tissue and is to remain on the tissue.

13 . The antiseptic composition for use according to claim 12 , wherein the antiseptic composition is to be applied prior to surgery, catheterization, or needle puncture.

14 . Use of a hydroxycarboxylic acid buffer for the preparation of an antiseptic composition for disinfecting tissue, wherein the antiseptic composition is as defined in claim 1 .

15 . The use according to claim 14 , wherein the tissue is skin or mucosal tissue.

16 . The use according to claim 15 , wherein the mucosal tissue is nasal or vaginal tissue.

17 . The use according to claim 16 , wherein the mucosal tissue is nasal tissue.

18 . The use according to claim 14 , wherein the antiseptic composition is to be directly applied to the tissue and is to remain on the tissue.

19 . The use according to claim 14 , wherein the antiseptic composition is to be applied prior to surgery, catheterization, or needle puncture.

Assignees

• 3M Innovative Properties Co

Inventors

• Scholz Matthew T
• Wang Danli
• Lu Triet M
• Zhu Dong-Wei

Classifications

• A61P31/02

  Local antiseptics · CPC title

• A61K47/12

  Carboxylic acids; Salts or anhydrides thereof · CPC title

• A01N59/12 Primary

  Iodine, e.g. iodophors; Compounds thereof · CPC title

• A61K31/79 Primary

  Polymers of vinyl pyrrolidone · CPC title