Magnetic particle manipulation apparatus

Patent metadata

Field	Value
Publication number	US-2016180998-A1
Application number	US-201514972102-A
Country	US
Kind code	A1
Filing date	Dec 17, 2015
Priority date	Dec 22, 2014
Publication date	Jun 23, 2016
Grant date	—

Abstract

The invention relates to a magnetic particle manipulation apparatus for moving magnetic particles within a tubular device, wherein the tubular device includes a gel-like medium layer and a liquid layer alternately stacked within a vessel and is filled with the magnetic particles. The magnetic particle manipulation apparatus of the invention includes a vessel holding portion, a vessel pressing portion and a magnetic field applying portion. The magnetic field applying portion includes a magnetic force source. At least one of the magnetic field applying portion and the vessel holding portion includes a moving mechanism capable of moving the magnetic force source. The vessel is pressed by the vessel pressing portion. The magnetic force source is moved relatively to the vessel holding portion by the moving mechanism, so as to move the magnetic particles.

First claim

What is claimed is:

1 . A magnetic particle manipulation apparatus for moving magnetic particles within a tubular device, wherein the tubular device comprises a gel-like medium layer and a liquid layer alternately stacked within a vessel and is filled with the magnetic particles, the magnetic particle manipulation apparatus comprising:
a vessel holding portion for holding the vessel; a vessel pressing portion for pressing the vessel to the vessel holding portion; and a magnetic field applying portion, wherein the magnetic field applying portion comprises a magnetic force source; at least one of the vessel holding portion and the magnetic field applying portion comprises a moving mechanism moving the magnetic force source relatively to the vessel holding portion in a uniaxial direction; the vessel is pressed by the vessel pressing portion in a direction orthogonal to the uniaxial direction, such that the vessel is fixed onto a receiving surface of the vessel holding portion parallel to the uniaxial direction; and the magnetic force source is moved relatively to the vessel holding portion in the uniaxial direction by the moving mechanism, so as to move the magnetic particles within the vessel in a longitudinal direction of the vessel.

2 . The magnetic particle manipulation apparatus according to claim 1 , wherein the vessel is held in a manner that the longitudinal direction of the vessel is parallel to the uniaxial direction.

3 . The magnetic particle manipulation apparatus according to claim 1 , wherein the vessel holding portion is disposed between the vessel pressing portion and the magnetic field applying portion.

4 . The magnetic particle manipulation apparatus according to claim 1 , wherein the vessel holding portion has a gap in a portion equivalent to a movement region of the magnetic force source within a portion opposed to the magnetic force source.

5 . The magnetic particle manipulation apparatus according to claim 1 , wherein the vessel holding portion comprises a nonmagnetic material.

Assignees

• Shimadzu Corp

Inventors

• Kanai Masaki
• Ohashi Tetsuo

Classifications

• B01L2200/0668

  Trapping microscopic beads · CPC title

• B03C2201/26

  for use in medical or biological applications · CPC title

• B03C2201/18

  Magnetic separation whereby the particles are suspended in a liquid · CPC title

• B01L9/06

  Test-tube stands; Test-tube holders · CPC title

• B01L3/502

  with fluid transport, e.g. in multi-compartment structures · CPC title