Data processing device for chromatograph and data processing method for chromatograph

Patent metadata

Field	Value
Publication number	US-2016169848-A1
Application number	US-201314902638-A
Country	US
Kind code	A1
Filing date	Aug 5, 2013
Priority date	Aug 5, 2013
Publication date	Jun 16, 2016
Grant date	—

Abstract

There are provided a data processing device for chromatograph and a data processing method for chromatograph which allow a peak to be desirably checked. A peak (correction target peak (P 1 )) whose intensity exceeds a predetermined threshold in a chromatogram at a target wavelength (X 1 ) is corrected based on correction reference values (height (H 1 ) and area (A 1 ) of a peak (P 11 )) and a sensitivity coefficient (R=I 1 /I 2 ), and the chromatogram after correction is displayed or printed. Therefore, even if the correction target peak (P 1 ) is saturated, display or printing may be performed in a state where correction has been performed so that the chromatogram at the peak (P 1 ) is not cut off in the middle. Accordingly, at the time of display or printing of the chromatogram, a fine peak may be prevented from becoming too small, and also the correction target peak (P 1 ) may be prevented from being cut off in the middle, and thus the peaks may be desirably checked.

First claim

1 . A data processing device for chromatograph, the data processing device being for processing three-dimensional data representing a relationship between time, wavelength and intensity obtained by an analysis of a sample by the chromatograph, the data processing device comprising:
a correction target peak detection unit for detecting, as a correction target peak, a peak whose intensity exceeds a predetermined threshold in a chromatogram at a target wavelength; a correction reference value calculation unit for calculating, as a correction reference value, at least one of a height and an area of a peak, corresponding to the correction target peak, in a chromatogram at a correction reference wavelength different from the target wavelength; a sensitivity coefficient calculation unit for calculating, as a sensitivity coefficient, a ratio between intensity at the target wavelength and intensity at the correction reference wavelength based on a spectrum at a time different from a retention time of the correction target peak; a peak correction processing unit for correcting the correction target peak based on the correction reference value and the sensitivity coefficient; and an output processing unit for causing a chromatogram at the target wavelength for which the correction target peak has been corrected by the peak correction processing unit to be displayed or printed.

2 . The data processing device for chromatograph according to claim 1 , wherein the output processing unit outputs the correction target peak corrected by the peak correction processing unit in a different display mode or a different print mode from another part of the chromatogram.

3 . A data processing method for chromatograph, the data processing method being for processing three-dimensional data representing a relationship between time, wavelength and intensity obtained by an analysis of a sample by the chromatograph, the data processing method comprising:
a correction target peak detection step of detecting, as a correction target peak, a peak whose intensity exceeds a predetermined threshold in a chromatogram at a target wavelength; a correction reference value calculation step of calculating, as a correction reference value, at least one of a height and an area of a peak, corresponding to the correction target peak, in a chromatogram at a correction reference wavelength different from the target wavelength; a sensitivity coefficient calculation step of calculating, as a sensitivity coefficient, a ratio between intensity at the target wavelength and intensity at the correction reference wavelength based on a spectrum at a time different from a retention time of the correction target peak; a peak correction processing step of correcting the correction target peak based on the correction reference value and the sensitivity coefficient; and an output processing step of causing a chromatogram at the target wavelength for which the correction target peak has been corrected in the peak correction processing step to be displayed or printed.

4 . The data processing method for chromatograph according to claim 3 , wherein, in the output processing step, the correction target peak corrected in the peak correction processing step is output in a different display mode or a different print mode from another part of the chromatogram.

Assignees

• Shimadzu Corp

Inventors

• Kamata Etsuho
• Yanagisawa Toshinobu
• Mito Yasuhiro
• Mishima Kenichi

Classifications

• G01N30/8634 Primary

  Peak quality criteria · CPC title