Computer-based analysis of oscillatory ventilation

Patent metadata

Field	Value
Publication number	US-2016166176-A1
Application number	US-201414907364-A
Country	US
Kind code	A1
Filing date	Jul 23, 2014
Priority date	Jul 25, 2013
Publication date	Jun 16, 2016
Grant date	—

Abstract

This document provides systems and techniques that can be used to provide computer-implemented interpretation (e.g., up-to-date, on demand, and real time interpretation) of respiratory profiles of patients using, for example, an application provided by a computer server system, to assess a patient's cardiac and/or pulmonary function.

First claim

What is claimed is:

1 . A computer-implemented method, wherein said method comprises:
(a) accessing, by a computer system, cardiopulmonary data for a patient; (b) identifying, using an oscillation period operation, periods of oscillation from the cardiopulmonary data for the patient; (c) identifying, using peak detection operation, amplitudes of oscillation from the cardiopulmonary data for the patient; (d) determining, by the computer system, one or more breathing patterns for the patient based on (i) the identified periods of oscillation and (ii) the identified amplitudes of oscillation; and (e) outputting, by the computer system, information that identifies the one or more breathing patterns.

2 . The computer-implemented method of claim 1 , wherein the oscillation period operation comprises a sine wave fitting operation that identifies the periods of oscillation.

3 . The computer-implemented method of claim 1 , wherein the oscillation period operation comprises Fourier analysis operation that identifies the periods of oscillation.

4 . The computer-implemented method of claim 1 , wherein the cardiopulmonary data for the patient corresponds to measurements that were taken over a period of time while the patient was exercising.

5 . The computer-implemented method of claim 1 , wherein the cardiopulmonary data for the patient corresponds to measurements that were taken over a period of time while the patient was resting.

6 . The computer-implemented method of claim 1 , wherein the cardiopulmonary data comprises spirometry and gas exchange values for the patient.

7 . The computer-implemented method of claim 1 , wherein the one or more breathing patterns comprise cyclic patterns in breath-by-breath ventilation and gas exchange.

8 . The computer-implemented method of claim 1 , wherein the determining comprises curve fitting the cardiopulmonary data for the patient by combining the periods of oscillation that are identified using the oscillation period operation with the amplitudes of oscillation that are identified using the peak detection operation.

9 . The computer-implemented method of claim 1 , wherein the peak detection operation comprises:
(a) for each data point in the cardiopulmonary data, generating a list that includes at least a threshold number of adjacent data points that occur earlier and later in time within the cardiopulmonary data; (b) sorting the generated list; (c) discarding data points in the generated list have the greatest and lowest values to generate a resulting list; (d) identifying local minima and maxima from the resulting list; (e) determining time differences and magnitude differences between the local minima and maxima; and (f) averaging the time differences and the magnitude differences to determine magnitude and period values from the cardiopulmonary data.

Assignees

• Mayo Foundation

Inventors

• Johnson Bruce D
• Olson Thomas P

Classifications

• A61B5/7257

  using Fourier transforms · CPC title

• A61B5/087

  Measuring breath flow · CPC title

• A61B5/7275

  Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor · CPC title

• A61B5/091 Primary

  Measuring volume of inspired or expired gases, e.g. to determine lung capacity · CPC title

• A61B5/083

  Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption · CPC title