Method for the preparation of a cell culture insert with at least one membrane
US-12162212-B2 · Dec 10, 2024 · US
US2016151979A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016151979-A1 |
| Application number | US-201514945993-A |
| Country | US |
| Kind code | A1 |
| Filing date | Nov 19, 2015 |
| Priority date | Nov 24, 2014 |
| Publication date | Jun 2, 2016 |
| Grant date | — |
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The invention relates to a method and a device for three-dimensional color printing, wherein at least a first printing material with a first printing material color and at least another printing material with another printing material color is used to construct a printing object ( 7 ), wherein an arrangement of the printing materials in a surface region and a near surface interior region of the printing object ( 7 ) is determined based on a desired color reproduction of the printing object.
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1 . A method for three-dimensional color printing, wherein at least a first printing material with a first printing material color and at least another printing material with another printing material color is used to construct a printing object ( 7 ), wherein an arrangement of the printing materials in a surface region and a near surface interior region of the printing object ( 7 ) is determined based on a desired color reproduction of the printing object ( 7 ). 2 . The method according to claim 1 , characterized in that a surface layer voxel set and a near-surface interior voxel set are determined, wherein the surface layer voxel set comprises all surface voxels, wherein one of the printing materials is assigned to each surface voxel, wherein one of the printing materials is assigned to each near-surface interior voxel, wherein the assignment of a printing material to a voxel is based on a desired color reproduction of the printing object. 3 . The method according to claim 2 , characterized in that for each voxel of at least the surface layer voxel set, a printing material color quantization is performed, wherein for each printing material color, a minimal or maximal color value is assigned to the respective voxel, wherein a color error value is distributed among voxels within a predetermined neighborhood of the respective voxel, wherein the assignment of a printing material to the respective voxel is based on a set of quantized printing material colors. 4 . The method according to claim 2 , characterized in that at least one interior layer voxel set of the printing object is determined, wherein the distances of all voxels of the interior layer voxel set to a respective closest surface voxel are within a predetermined distance interval, wherein to each voxel of the interior layer voxel set a printing material color vector of the closest surface voxel is assigned. 5 . The method according to claim 3 , characterized in that for each surface voxel of the surface layer voxel set, a set of non-quantized neighboring interior voxels is determined, wherein a subset with a limited number of closest non-quantized neighboring interior voxels is selected, wherein a single maximal color value of the set of quantized printing material colors of the surface voxel is assigned to each non-quantized neighboring interior voxel of the subset in an alternating way. 6 . The method according to claim 2 , characterized in that the voxels of at least the surface layer voxel set are traversed in at least one run, wherein the next voxel in the traversal is determined depending on the value of a distance-to-empty function of the next voxel. 7 . The method according to claim 6 , characterized in that a slice-dependent subset of a layer voxel set is determined, wherein the voxels of the slice-dependent subset are traversed in at least one run. 8 . The method according to claim 6 , characterized in that all voxels of the remaining untraversed voxels are determined at which a surface normal is oriented downwards, wherein a starting voxel for a run is determined as the voxel with a maximal distance to the closest exterior voxel or all voxels of the remaining untraversed voxels are determined at which a surface normal is oriented upwards, wherein a starting voxel for a run is determined as the voxel with a minimal distance to the closest exterior voxel. 9 . The method according to claim 6 , characterized in that a desired traversal direction orientation is reversed in a following run and/or a following slice. 10 . The method according to claim 3 , characterized in that the surface layer voxel set and at least one interior layer voxel set are processed in parallel. 11 . The method according to claim 1 , characterized in that at least one support material ( 6 ) with a support material color is used as an additional printing material, wherein the at least one support material color is selected such that a color gamut (CS) defined by the printing material color(s) is extended. 12 . The method according to claim 11 , characterized in that support material ( 6 ) is only used to construct or provide an interior voxel ( 8 ). 13 . The method according to claim 11 , characterized in that an arrangement of printing material and support material is provided such that a number of voxels of a set of connected support material voxels (V 6 ) is smaller than a predetermined support material voxel number if at least one of the support material voxels (V 6 ) is a surface layer voxel ( 10 ). 14 . The method according to claim 11 , characterized in that an arrangement of print material and support material is provided such that the spatial frequency spectrum of support material voxels (V 6 ) has spectral components for non-zero frequencies whose absolute values are larger than zero. 15 . The method according to claim 11 , characterized in that an arrangement of printing material and support material ( 6 ) is provided such that a translucence of the object voxels along an optical path ( 11 ) between a support material voxel (V 6 ) and a printing object environment is higher than a desired threshold value. 16 . The method according to claim 11 , characterized in that a percentage of support material ( 6 ) used to construct the printing object ( 7 ) and/or a predetermined volume fraction of the printing object ( 7 ) is smaller than a predetermined threshold value. 17 . The method according to claim 11 , characterized in that the printing process is at least partially controlled by a printing material color vector, wherein the maximum admissible support material color value of the support material color-related entry is smaller than the maximum admissible printing material color value of the printing material color-related entries. 18 . A three-dimensional color printing device, wherein the printing device ( 1 ) comprises a means for printing a first printing material with a first printing material color, a means for printing at least one other printing material with another printing material color and at least one control unit ( 8 ), wherein the means for printing the first printing material is controlled such that the first printing material is used to construct a printing object ( 7 ), wherein the means for printing the at least one other printing material is controlled such that the at least one other printing material is used to construct the printing object ( 7 ), characterized in that the means for printing the first printing material and the at least one other printing material are controlled such that an arrangement of the printing materials in a surface region and a near surface interior region of the printing object ( 7 ) is provided such that a desired color reproduction of the printing object ( 7 ) is provided. 19 . The method according to claim 3 , characterized in that at least one interior layer voxel set of the printing object is determined, wherein the distances of all voxels of the interior layer voxel set to a respective closest surface voxel are within a predetermined distance interval, wherein to each voxel of the interior layer voxel set a printing material color vector of the closest surface voxel is assigned. 20 . A method for three-dimensional color printing, wherein at least a first printing material with a first printing material color and at least another printing material with another printing material color is used to construct a printing object ( 7 ), wherein an arrangement of the printing materials in a surface region and a near surface interior
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