Crispr/cas-related methods and compositions for knocking out c5
US-2024415980-A1 · Dec 19, 2024 · US
Camelid single heavy-chain antibody directed against chromatin and uses of same
US2016145352A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016145352-A1 |
| Application number | US-201414899695-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jun 20, 2014 |
| Priority date | Jun 21, 2013 |
| Publication date | May 26, 2016 |
| Grant date | — |
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Abstract
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Disclosed is a polypeptide including a single-domain antibody directed against chromatin, derived from a heavy-chain antibody devoid of a camelid light chain (VHH) and capable of binding specifically with a complex of H2A and H2B histones. This polypeptide is particularly suitable for detecting/viewing chromatin in real time, without interfering with the rate of cell proliferation.
First claim
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1 - 21 . (canceled) 22 . A polypeptide comprising a single-domain antibody directed against chromatin, derived from a heavy-chain antibody naturally devoid of a light chain (VHH) of a camelid and capable of binding specifically to a complex of H2A and H2B histones. 23 . A polypeptide as claimed in claim 22 , wherein said single-domain antibody has the amino acid sequence of any one of the sequences SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 or SEQ ID No…
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- What does patent US2016145352A1 cover?
- Disclosed is a polypeptide including a single-domain antibody directed against chromatin, derived from a heavy-chain antibody devoid of a camelid light chain (VHH) and capable of binding specifically with a complex of H2A and H2B histones. This polypeptide is particularly suitable for detecting/viewing chromatin in real time, without interfering with the rate of cell proliferation.
- Who is the assignee on this patent?
- Agronomique Inst Nat Rech, Univ Toulouse 3 Paul Sabatier
- What technology area does this patent fall under?
- Primary CPC classification C07K16/18. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu May 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).