Compositions and methods for immunotherapy
US-2015376296-A1 · Dec 31, 2015 · US
US2016145347A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016145347-A1 |
| Application number | US-201514961152-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 7, 2015 |
| Priority date | Dec 16, 2009 |
| Publication date | May 26, 2016 |
| Grant date | — |
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Disclosed herein are antibodies that detect a lipid-like antigen on prostate cancer cells and methods of detecting and treating prostate cancer using the same.
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1 .- 21 . (canceled) 22 . An antibody or antibody functional fragment that binds to B-III dodecaosylceramide or B-IV tetradecaosylceramide; provided that the antibody is not F77 MAb. 23 . The antibody or antibody functional fragment of claim 22 wherein said antibody or antibody functional fragment competes for binding with F77 MAb. 24 . The antibody or antibody functional fragment of claim 23 wherein said antibody or antibody functional fragment competes for binding with F77 MAb to B-III dodecaosylceramide or B-IV tetradecaosylceramide. 25 .- 33 . (canceled)
specific for metastasis · CPC title
Antibody-dependent cellular cytotoxicity [ADCC] · CPC title
Antineoplastic agents · CPC title
Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation · CPC title
Reproductive system, e.g. ovaria, uterus, testes, prostate · CPC title
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