Devices and systems for chromatography column bed support management and related methods
US-2024241089-A1 · Jul 18, 2024 · US
US2016136543A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016136543-A1 |
| Application number | US-201414897844-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jun 19, 2014 |
| Priority date | Jul 5, 2013 |
| Publication date | May 19, 2016 |
| Grant date | — |
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An object of the present invention is to separate a material to be separated at a low cost and constant accuracy when the material to be separated is separated from a mobile phase containing the material to be separated through the passing of the mobile phase through a stationary phase, even if the mobile phase has a large volume. A separation device characterized in that a separation column provided with a stationary phase having a volume capable of processing the entire volume of a mobile phase containing a material to be separated is provided, the separation column is replaceable, and the usage count of the stationary phase reaches a lifetime count through the processing of one batch.
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1 . A separation device characterized by comprising a separation column provided with a stationary phase having a volume capable of processing an entire volume of mobile phase containing a material to be separated, the separation column being replaceable, wherein a usage count of the stationary phase reaches a lifetime count by one batch process. 2 . The separation device according to claim 1 , characterized in that the separation column is composed of plural columns provided with the stationary phase, and a total volume of the stationary phase filled in the plural columns is a volume capable of processing the entire volume of the mobile phase containing the material to be separated. 3 . The separation device according to claim 2 , characterized by further comprising: a plurality of pipes respectively connected to each of the plural columns; a plurality of switching valves respectively provided on the plurality of pipes; and a control device for controlling communications between the pipes by the plurality of switching valves. 4 . The separation device according to claim 2 , characterized in that a total of column bed heights of the plural columns is a column bed height when the stationary phase having the above volume is a single column. 5 . The separation device according to claim 1 , characterized in that the volume of the stationary phase is determined based on a total amount of the material to be separated contained in the mobile phase, and a maximum adsorption capacity of the stationary phase.
relating to the construction of the column · CPC title
placed in parallel · CPC title
relating to the conditioning of the sorbent material · CPC title
Simulated moving beds · CPC title
biological materials · CPC title
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