Activity delivery progress monitor

Patent metadata

Field	Value
Publication number	US-2016136453-A1
Application number	US-201615003980-A
Country	US
Kind code	A1
Filing date	Jan 22, 2016
Priority date	Jun 4, 2010
Publication date	May 19, 2016
Grant date	—

Abstract

A system and method for monitoring progress of a radiopharmaceutical injection procedure includes: measuring and monitoring radiopharmaceutical activity of a radiopharmaceutical remaining in at least a portion of a disposable administration set used with a radiopharmaceutical fluid delivery system; and displaying the radiopharmaceutical activity remaining in at least the portion of the disposable administration set to an operator.

First claim

What is claimed is:

1 . A method for monitoring progress of a radiopharmaceutical injection procedure comprising:
measuring and monitoring radiopharmaceutical activity of a radiopharmaceutical remaining in a portion of a disposable administration set used with a radiopharmaceutical fluid delivery device, wherein the measuring and monitoring are performed during the radiopharmaceutical injection procedure; displaying on a wireless display device the radiopharmaceutical activity remaining in the portion of the disposable administration set, wherein the displaying is performed during the radiopharmaceutical injection procedure; and providing an alert on the wireless display device that a delivery issue has occurred if the radiopharmaceutical activity remaining in the portion of the disposable administration set differs from an expected value of radiopharmaceutical activity remaining in the portion of the disposable administration set at a given time.

2 . The method of claim 1 , wherein the delivery issue is an occlusion in the disposable administration set.

3 . The method of claim 1 , further comprising:
automatically adjusting at least one of saline volume and saline flow rate to the disposable administration set to flush the radiopharmaceutical remaining in the portion of the disposable administration set if the delivery issue occurs.

4 . The method of claim 3 , further comprising:
ending the radiopharmaceutical injection procedure in response to failing to cure the delivery issue by the automatically adjusting at least one of saline volume and saline flow rate.

5 . The method of claim 1 , wherein the measured radiopharmaceutical activity of the radiopharmaceutical remaining in the portion of the disposable administration set is the measured activity as a function of at least one of time, flow rate, and volume.

6 . The method of claim 1 , wherein the radiopharmaceutical fluid delivery device comprises:
the disposable administration set is a multi-patient disposable administration set operable to allow fluid flow from a radiopharmaceutical source of the radiopharmaceutical fluid delivery device to one or more patients; an activity measuring unit operable to determine a level of radioactivity within the portion of the disposable administration set; a control unit operatively coupled to the activity measuring unit operable to convert activity measurements taken by the activity measuring unit to a representation of the radiopharmaceutical activity remaining in the portion of the disposable administration set; and a display unit operatively coupled to the control unit operable to display the radiopharmaceutical activity remaining in the portion of the disposable administration set.

7 . The method of claim 1 , wherein the disposable administration set comprises:
a medical fluid component; a radiopharmaceutical component; a coil component coupled to the medical fluid component and the radiopharmaceutical component; and a waste component coupled to the medical fluid component, the coil component, and the radiopharmaceutical component.

8 . The method of claim 7 , wherein the coil component is the portion of the disposable administration set that is configured to have the radiopharmaceutical activity of the radiopharmaceutical remaining therein measured and monitored.

9 . A method of determining a flow rate of a radiopharmaceutical fluid in an injection system comprising:
pumping a radiopharmaceutical fluid from an ionization chamber by adding saline to the ionization chamber; continuously monitoring the radioactivity of the radiopharmaceutical fluid in the ionization chamber to determine a plurality of measured activity values; determining a slope of radioactive emissions based on the plurality of measured activity values to determine an emissions slope; and determining a rate at which the radiopharmaceutical fluid is replaced by the saline based on the emissions slope and the volume of the chamber, wherein the rate at which the radiopharmaceutical fluid is replaced by the saline corresponds to a flow rate of the radiopharmaceutical fluid.

10 . The method of claim 10 , wherein the flow rate of the radiopharmaceutical fluid passing through the disposable administration set is determined using a linear regression model.

11 . The method of claim 10 , wherein the disposable administration set comprises:
a medical fluid component; a radiopharmaceutical fluid component; a coil component coupled to the medical fluid component and the radiopharmaceutical fluid component; and a waste component coupled to the medical fluid component, the coil component, and the radiopharmaceutical fluid component.

12 . The method of claim 10 , wherein the continuous monitoring the radioactivity activity of the radiopharmaceutical fluid remaining in the ionization chamber is performed by one or more of a CZT crystal detector, a Geiger-Müller counter, and a scintillating counter.

13 . A method of determining a flow rate of a radiopharmaceutical fluid in an injection system during an injection procedure comprising:
measuring and monitoring radiopharmaceutical activity of the radiopharmaceutical fluid remaining in a portion of a disposable administration set used with a radiopharmaceutical fluid delivery system to determine a plurality of radiopharmaceutical activity values during the injection procedure; and determining a flow rate of the radiopharmaceutical fluid passing through the disposable administration set.

14 . The method of claim 13 , wherein the flow rate of the radiopharmaceutical fluid passing through the disposable administration set is determined using a linear regression model.

15 . The method of claim 13 , further comprising:
determining a location of the radiopharmaceutical fluid within the disposable administration set based on the flow rate of the radiopharmaceutical fluid passing through the disposable administration set.

16 . The method of claim 15 , further comprising:
automatically adjusting parameters of the injection procedure based on the location of the radiopharmaceutical fluid within the disposable administration set.

17 . The method of claim 13 , wherein the measuring and monitoring of the radiopharmaceutical activity of a radiopharmaceutical fluid remaining in a portion of a disposable administration set is performed by one of an ionization chamber, a CZT crystal detector, a Geiger-Müller counter, and a scintillating counter.

18 . The method of claim 13 , wherein the disposable administration set comprises:
a medical fluid component; a radiopharmaceutical fluid component; a coil component coupled to the medical fluid component and the radiopharmaceutical fluid component; and a waste component coupled to the medical fluid component, the coil component, and the radiopharmaceutical fluid component.

Assignees

• Bayer Healthcare Llc

Inventors

• Agamaite James A
• Griffith Scott R
• Descalzi Douglas
• Marsh Charles

Classifications

• A61N5/1064

  for adjusting radiation treatment in response to monitoring · CPC title

• A61N5/1071

  for verifying the dose delivered by the treatment plan · CPC title

• A61N5/1001 Primary

  using radiation sources introduced into or applied onto the body; brachytherapy · CPC title

• A61N2005/1021

  Radioactive fluid · CPC title

• A61N5/00 Primary

  Radiation therapy (ultrasound therapy A61N7/00; devices or apparatus applicable to both therapy and diagnosis A61B6/00) · CPC title