Tunable anti-microbial loaded hydrogels

US2016136232A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2016136232-A1
Application numberUS-201514942435-A
CountryUS
Kind codeA1
Filing dateNov 16, 2015
Priority dateNov 14, 2014
Publication dateMay 19, 2016
Grant date

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Abstract

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A tunable antimicrobial-loaded hydrogel formulation has a mechanical strength can be altered by changing the salt composition. The hydrogel formulation is preferably a Gellan film. The ion concentration in the gel material may be altered to obtain the desired gel strength. The hydrogel formulation is layered directly upon a skin area such as burnt skin. The hydrogel formulation includes a dosage of free antibiotic, such as the antibiotic is preferably vancomycin, for rapid release. The hydrogel formulation also includes microparticles and/or nanoparticles such as activated carbon powder that has adsorbed additional antibiotic. The particles are used to aid in attaining a timely or sustained release of the antibiotic drug.

First claim

Opening claim text (preview).

What is claimed is: 1 . A hydrogel formulation comprising: a hydrogel having a particular mechanical strength; and a salt composition for altering the mechanical strength. 2 . A hydrogel formulation as recited in claim 1 , further comprising a compound selected from the group consisting of an antibiotic (gentamicin, clindamycin etc.), an antifungal compound, an anti-inflammatory compound, a proteins (growth factors) and enzymes to promote wound healing…

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What does patent US2016136232A1 cover?
A tunable antimicrobial-loaded hydrogel formulation has a mechanical strength can be altered by changing the salt composition. The hydrogel formulation is preferably a Gellan film. The ion concentration in the gel material may be altered to obtain the desired gel strength. The hydrogel formulation is layered directly upon a skin area such as burnt skin. The hydrogel formulation includes a dosag…
Who is the assignee on this patent?
Univ Brown
What technology area does this patent fall under?
Primary CPC classification A61K9/0014. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu May 19 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).