Systems and methods for treatment of hearing using dihexa
US-2024424050-A1 · Dec 26, 2024 · US
US2016136232A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016136232-A1 |
| Application number | US-201514942435-A |
| Country | US |
| Kind code | A1 |
| Filing date | Nov 16, 2015 |
| Priority date | Nov 14, 2014 |
| Publication date | May 19, 2016 |
| Grant date | — |
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A tunable antimicrobial-loaded hydrogel formulation has a mechanical strength can be altered by changing the salt composition. The hydrogel formulation is preferably a Gellan film. The ion concentration in the gel material may be altered to obtain the desired gel strength. The hydrogel formulation is layered directly upon a skin area such as burnt skin. The hydrogel formulation includes a dosage of free antibiotic, such as the antibiotic is preferably vancomycin, for rapid release. The hydrogel formulation also includes microparticles and/or nanoparticles such as activated carbon powder that has adsorbed additional antibiotic. The particles are used to aid in attaining a timely or sustained release of the antibiotic drug.
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What is claimed is: 1 . A hydrogel formulation comprising: a hydrogel having a particular mechanical strength; and a salt composition for altering the mechanical strength. 2 . A hydrogel formulation as recited in claim 1 , further comprising a compound selected from the group consisting of an antibiotic (gentamicin, clindamycin etc.), an antifungal compound, an anti-inflammatory compound, a proteins (growth factors) and enzymes to promote wound healing…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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