Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines
US-9242994-B2 · Jan 26, 2016 · US
Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines
US2016136142A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016136142-A1 |
| Application number | US-201615004847-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jan 22, 2016 |
| Priority date | Mar 23, 2012 |
| Publication date | May 19, 2016 |
| Grant date | — |
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Abstract
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Methods for inhibiting the growth of pancreatic cancer cells or other cancer cells driven by Sonic hedgehog are disclosed. The method involves exposing the cells to 5-acyl-6,7-dihydrothieno[3,2-c]pyridines of formula I
First claim
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1 . A method for treating a patient having an Shh-driven cancer comprising administering to said patient a therapeutically effective amount of a compound of formula: or a pharmaceutically acceptable salt thereof; wherein: R 1 and R 2 are independently hydrogen, halogen, (C 1 -C 4 )hydrocarbyl, (C 1 -C 4 )alkoxy, trifluoromethyl, trifluoromethoxy, cyano, or nitro; R 3 is (C 1…
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Human Necessities · mapped topic
Human Necessities · mapped topic
- C07D495/04Primary
Chemistry & Metallurgy · mapped topic
- A61K31/4365Primary
Human Necessities · mapped topic
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- What does patent US2016136142A1 cover?
- Methods for inhibiting the growth of pancreatic cancer cells or other cancer cells driven by Sonic hedgehog are disclosed. The method involves exposing the cells to 5-acyl-6,7-dihydrothieno[3,2-c]pyridines of formula I
- Who is the assignee on this patent?
- Sloan Kettering Inst Cancer, Univ Rockefeller
- What technology area does this patent fall under?
- Primary CPC classification C07D495/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu May 19 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).