Drug for treatment of nonalcoholic fatty liver disease

US2016136138A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2016136138-A1
Application numberUS-201414903114-A
CountryUS
Kind codeA1
Filing dateJul 9, 2014
Priority dateJul 10, 2013
Publication dateMay 19, 2016
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention provides a compound useful in the prevention and treatment of nonalcoholic fatty liver disease. The invention relates to a drug for the prevention and/or treatment of nonalcoholic fatty liver disease, the drug having as an active ingredient (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy]butyric acid, a salt thereof, or a solvate of these.

First claim

Opening claim text (preview).

1 - 4 . (canceled) 5 . A method for preventing and/or treating nonalcoholic fatty liver disease, comprising: administering an effective amount of (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy]butyric acid or a salt thereof, or a solvate thereof to a patient in need thereof. 6 . The method of claim 5 , wherein the nonalcoholic fatty liver disease is nonalcoholic steatohepatitis. 7 . A method for suppressing or reducing fat deposition in the liver, comprising: administering an effective amount of (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy]butyric acid or a salt thereof, or a solvate thereof to a patient in need of suppression or reduction of fat deposition in the liver 8 . A method for suppressing the increase in the number of Kupffer cells in the liver or reducing the number of Kupffer cells in the liver, comprising: administering an effective amount of (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy]butyric acid or a salt thereof, or a solvate thereof to a patient in need of suppression of the increase in the number of Kupffer cells in the liver or in need of reduction of the number of Kupffer cells in the liver.

Assignees

Inventors

Classifications

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • A61P1/16Primary

    for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics · CPC title

  • A61K31/423Primary

    condensed with carbocyclic rings · CPC title

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What does patent US2016136138A1 cover?
The present invention provides a compound useful in the prevention and treatment of nonalcoholic fatty liver disease. The invention relates to a drug for the prevention and/or treatment of nonalcoholic fatty liver disease, the drug having as an active ingredient (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy]butyric acid, a salt thereof, or a solvate of these.
Who is the assignee on this patent?
Kowa Co
What technology area does this patent fall under?
Primary CPC classification A61P1/16. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu May 19 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).