Injection Device

Patent metadata

Field	Value
Publication number	US-2016129199-A1
Application number	US-201414897347-A
Country	US
Kind code	A1
Filing date	Jun 11, 2014
Priority date	Jun 11, 2013
Publication date	May 12, 2016
Grant date	—

Abstract

An injection device comprising a housing adapted to receive a syringe having a discharge nozzle, and a sliding component which protrudes, when in a first position, from the aperture in the housing, wherein the sliding component is movable into the housing into a second position, wherein the sliding component comprises a contact surface located at a first end of the sliding component which protrudes from the housing when the sliding component is in its first position.

First claim

1 . An injection device comprising:
a housing adapted to receive a syringe having a discharge nozzle, the syringe being moveable in the housing on actuation of the injection device along a longitudinal axis from a retracted position in which the discharge nozzle is contained within the housing and an extended position in which the discharge nozzle of the syringe extends from the housing through an exit aperture; a sliding component which protrudes, when in a first position, from the aperture in the housing, wherein the sliding component is movable into the housing into a second position, wherein the sliding component comprises a contact surface located at a first end of the sliding component which protrudes from the housing when the sliding component is in its first position.

2 . A device according to claim 1 , wherein the sliding component is a sliding sleeve.

3 . A device according to claim 1 or claim 2 , further comprising:
an actuator; and
a drive adapted to be acted upon by the actuator and in turn act upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the discharge nozzle.

4 . A device according to any one of the preceding claims, wherein the sliding component is part of a locking mechanism moveable from an engaged position in a direction into the housing at the exit aperture into a disengaged position and adapted to prevent actuation of the device when it is in its engaged position and permit actuation of the device when it is in its disengaged position.

5 . A device according to any one of the preceding claims, wherein the contact surface comprises a flange.

6 . A device according to any one of the preceding claims, wherein the contact surface extends perpendicularly to a longitudinal axis of the sliding component.

7 . A device according to any one of the preceding claims, wherein the first end of the sliding component flares outwardly towards the contact surface.

8 . A device according to claim 7 , wherein the sliding component flares uniformly outwardly towards the contact surface.

9 . A device according to any one of the preceding claims, wherein the contact surface extends outwardly from the sliding component.

10 . A device according to any one of the preceding claims, wherein the contact surface is located on an exterior surface of the first end of the sliding component.

11 . A device according to any one of the preceding claims, wherein the contact surface extends inwardly from the sliding component.

12 . A device according to any one of the preceding claims, wherein the contact surface is located on an interior surface of the first end of the sliding component.

13 . A device according to any one of the preceding claims further comprising a cap removably located over the exit aperture.

14 . A device according to claim 13 , wherein the cap comprises a body and a sleeve located within the body and fixed relative to the body.

15 . A device according to claim 13 or claim 14 , wherein an interior of the cap is shaped to receive the contact surface.

16 . A device according to claim 15 , wherein the interior of the cap comprises at least one rib.

17 . A device according to claim 16 , wherein the interior of the cap comprises a plurality of ribs.

18 . A device according to claim 16 or claim 17 , wherein the at least one rib permits the cap to shapingly conform with the contact surface when the cap is over the exit aperture.

19 . A device according to any one of claims 16 to 18 , further comprising a retaining means on the housing and/or the cap for retaining the cap over the exit aperture.

20 . A device according to any one of the preceding claims wherein a first end of the housing closest to the contact surface is shaped to receive the contact surface when the sliding component is moved in a direction into the housing.

21 . A device according to any one of the preceding claims, wherein the contact surface is removable from the sliding component.

22 . A device substantially as hereinbefore described with reference to the accompanying drawings.

23 . An injection device according to any of the preceding claims containing a substance selected from the group consisting of:
golimumab, hormones, antitoxins, substances for the control of pain, substances for the control of thrombosis, substances for the control or elimination of infection, peptides, proteins, human insulin or a human insulin analogue or derivative, polysaccharide, DNA, RNA, enzymes, antibodies, oligonucleotide, antiallergics, antihistamines, anti-inflammatories, corticosteroids, disease modifying anti-rheumatic drugs, erythropoietin, or vaccines, for use in the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency, toxicity, pain, thrombosis, infection, diabetes mellitus, diabetic retinopathy, acute coronary syndrome, angina, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy, hay fever, inflammation, anaemia, or myelodysplasia, or in the expression of protective immunity.

24 . A substance selected from the group consisting of: golimumab, hormones, antitoxins, substances for the control of pain, substances for the control of thrombosis, substances for the control or elimination of infection, peptides, proteins, human insulin or a human insulin analogue or derivative, polysaccharide, DNA, RNA, enzymes, antibodies, oligonucleotide, antiallergics, antihistamines, anti-inflammatories, corticosteroids, disease modifying anti-rheumatic drugs, erythropoietin, or vaccines,
for use in the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency, toxicity, pain, thrombosis, infection, diabetes mellitus, diabetic retinopathy, acute coronary syndrome, angina, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy, hay fever, inflammation, anaemia, or myelodysplasia, or in the expression of protective immunity, by delivery of said substance to a human subject using an injection device according to any one of claims 1 to 22 .

25 . An injection device for use in the treatment or prevention rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency, toxicity, pain, thrombosis, infection, diabetes mellitus, diabetic retinopathy, acute coronary syndrome, angina, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy, hay fever, inflammation, anaemia, or myelodysplasia, or in the expression of protective immunity,
by delivery of a substance selected from the group consisting of: golimumab, hormones, antitoxins, substances for the control of pain, substances for the control of thrombosis, substances for the control or elimination of infection, peptides, proteins, human insulin or a human insulin analogue or derivative, polysaccharide, DNA, RNA, enzymes, antibodies, oligonucleotide, antiallergics, antihistamines, anti-inflammatories, corticosteroids, disease modifying anti-rheumatic drugs, erythropoietin, or vaccines, to a human subject by using the injection device, wherein the injection device is an injection device according to any one of claims 1 to 22 .

Assignees

• Cilag Gmbh Int

Inventors

• Bitar Ahmad
• Jennings Douglas Ivan

Classifications

• A61M2005/2006

  Having specific accessories · CPC title

• A61M2005/206

  With automatic needle insertion · CPC title

• A61M5/32

  Needles; Details of needles pertaining to their connection with syringe or hub (infusion needles A61M5/158); Accessories for bringing the needle into, or holding the needle on, the body {(A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065)}; Devices for protection of needles {(apparatus specially adapted for cleaning or sterilising needles A61M5/001)} · CPC title

• A61M2005/208

  Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin · CPC title

• A61M5/2033 Primary

  Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287) · CPC title