Sensor and Method for Removing Interfering Substance

Patent metadata

Field	Value
Publication number	US-2016123918-A1
Application number	US-201614991018-A
Country	US
Kind code	A1
Filing date	Jan 8, 2016
Priority date	Apr 16, 2010
Publication date	May 5, 2016
Grant date	—

Abstract

A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter.

First claim

1 .- 5 . (canceled)

6 . A sensor for measuring an objective substance contained in a sample, the sensor comprising:
a substrate; a detecting unit which is provided on the substrate and which detects the objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in the sample on the other hand; and a removing unit which removes the interfering substance adhered to the filter,
wherein:
the removing unit has at least a pair of removing electrodes which are arranged in mutual contact with the filter or closely to the filter; and
the interfering substance adhered to the filter is removed by means of electrolytic cleaning for the removing electrodes performed by applying a voltage between the removing electrodes.

7 . The sensor according to claim 6 , wherein the removing electrodes are arranged so that the interfering substance, which adheres to the removing electrodes and the filter, is formed while being joined or linked together.

8 .- 13 . (canceled)

14 . A method for removing an interfering substance to be a applied to a sensor comprising a detecting unit which is provided on a substrate and which detects an objective substance contained in a sample, the method comprising:
allowing the interfering substance to adhere to a filter beforehand by covering the detecting unit with the filter which permits permeation of the objective substance on one hand and which regulates permeation of the interfering substance contained in the sample on the other hand, and removing the interfering substance adhered to the filter by means of a removing unit which removes the interfering substance,
wherein:
the removing unit has at least a pair of removing electrodes which are arranged in mutual contact with the filter or closely to the filter; and
the interfering substance adhered to the filter is removed by means of electrolytic cleaning for the removing electrodes performed by applying a voltage between the removing electrodes.

15 . The method for removing the interfering substance according to claim 14 , wherein the removing electrodes are arranged so that the interfering substance, which adheres to the removing electrodes and the filter, is formed while being joined or linked together.

Assignees

• Arkray Inc

Inventors

• Shiraki Yasunori
• Katsuki Koji
• Iketani Kazuya

Classifications

• A61B5/14735

  comprising an immobilised reagent · CPC title

• C25F1/00

  Electrolytic cleaning, degreasing, pickling or descaling · CPC title

• G01N27/3272

  Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels (optical biosensors G01N33/52) · CPC title

• G01N27/3274 Primary

  Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration (coding of calibration information G01N33/48771) · CPC title

• G01N27/40

  Semi-permeable membranes or partitions · CPC title