Aerosol-generating system comprising a delivery enhancing compound source and a medicament source

Patent metadata

Field	Value
Publication number	US-2016120220-A1
Application number	US-201414890366-A
Country	US
Kind code	A1
Filing date	May 19, 2014
Priority date	May 21, 2013
Publication date	May 5, 2016
Grant date	—

Abstract

An aerosol-generating system is provided, including a medicament source and a volatile delivery enhancing compound source. The volatile delivery enhancing compound source includes a first sorption element, a second sorption element downstream of the first sorption element, and a volatile delivery enhancing compound sorbed on the first sorption element and the second sorption element, wherein a rate of release of the volatile delivery enhancing compound from the first sorption element is greater than a rate of release of the volatile delivery enhancing compound from the second sorption element.

First claim

1 . An aerosol-generating system, comprising:
a medicament source; and a volatile delivery enhancing compound source, comprising:
a first sorption element;
a second sorption element downstream of the first sorption element; and
a volatile delivery enhancing compound sorbed on the first sorption element and the second sorption element,
wherein a rate of release of the volatile delivery enhancing compound from the first sorption element is greater than a rate of release of the volatile delivery enhancing compound from the second sorption element.

2 . The aerosol-generating system according to claim 1 , wherein an air permeability of the first sorption element is greater than an air permeability of the second sorption element.

3 . The aerosol-generating system according to claim 1 , wherein a porosity of the first sorption element is greater than a porosity of the second sorption element.

4 . The aerosol-generating system according to claim 1 , wherein a polarity of the second sorption element is greater than a polarity of the first sorption element.

5 . The aerosol-generating system according to claim 1 , wherein the medicament source comprises:
a third sorption element; and a medicament sorbed on the first sorption element.

6 . The aerosol-generating system according to claim 5 , wherein the medicament comprises nicotine.

7 . The aerosol-generating system according to claim 1 , wherein the volatile delivery enhancing compound comprises an acid.

8 . The aerosol-generating system according to claim 7 , wherein the acid is selected from the group consisting of 3-methyl-2-oxovaleric acid, pyruvic acid, 2-oxovaleric acid, 4-methyl-2-oxovaleric acid, 3-methyl-2-oxobutanoic acid, 2-oxooctanoic acid, and combinations thereof.

9 . The aerosol-generating system according to claim 7 , wherein the acid is pyruvic acid.

10 . The aerosol-generating system according to claim 1 , wherein an amount of the volatile delivery enhancing compound sorbed on the first sorption element is greater than an amount of the volatile delivery enhancing compound sorbed on the second sorption element.

11 . The aerosol-generating system according to claim 1 , wherein the first sorption element is of substantially the same dimensions as the second sorption element.

12 . The aerosol-generating system according to claim 1 , wherein the second sorption element is immediately downstream of and in contact with the first sorption element.

13 . The aerosol-generating system according to claim 1 , wherein the second sorption element is spaced apart from the first sorption element.

14 . The aerosol-generating system according to claim 1 , further comprising:
an aerosol-generating article, comprising the medicament source and the volatile delivery enhancing compound source.

15 . The aerosol-generating system according to claim 14 , further comprising:
an aerosol-generating device in cooperation with the aerosol-generating article, the aerosol generating device comprising heating means for heating one or both of the medicament source and the volatile delivery enhancing compound source of the aerosol-generating article.

16 . (canceled)

17 . The aerosol-generating system according to claim 14 , wherein the aerosol-generating article further comprises:
a housing comprising:
an air inlet;
a first compartment in communication with the air inlet, the first compartment comprising a first one of the medicament source and the volatile delivery enhancing compound source;
a second compartment in communication with the first compartment, the second compartment comprising a second one of the medicament source and the volatile delivery enhancing compound source; and
an air outlet,
wherein the air inlet and the air outlet are in communication with each other and are configured so that air may pass into the housing through the air inlet, through the housing, and out of the housing through the air outlet.

18 . The aerosol-generating system according to claim 14 , wherein the aerosol-generating article further comprises:
a housing, comprising:
an air inlet;
a first compartment in communication with the air inlet, the first compartment comprising a first one of the medicament source and the volatile delivery enhancing compound source;
a second compartment in communication with the air inlet, the second compartment comprising a second one of the medicament source and the volatile delivery enhancing compound source; and
an air outlet,
wherein the air inlet and the air outlet are in communication with each other and are configured so that air may pass into the housing through the air inlet, through the housing and out of the housing through the air outlet.

19 . The aerosol-generating system according to claim 14 , wherein the aerosol-generating article further comprises:
a housing, comprising:
a first air inlet;
a second air inlet;
a first compartment in communication with the first air inlet, the first compartment comprising a first one of the medicament source and the volatile delivery enhancing compound source;
a second compartment in communication with the second air inlet, the second compartment comprising a second one of the medicament source and the volatile delivery enhancing compound source; and
an air outlet,
wherein the first air inlet, the second air inlet and the air outlet are in communication with each other and are configured so that air may pass into the housing through the first air inlet, through the housing, and out of the housing through the air outlet and air may pass into the housing through the second air inlet, through the housing, and out of the housing through the air outlet.

20 . The aerosol-generating system according to claim 17 , wherein one or both of the first compartment and the second compartment of the aerosol-generating article is sealed by one or more frangible seals.

21 . The aerosol-generating system according to claim 17 , wherein the first compartment comprises the volatile delivery enhancing compound source and the second compartment comprises the nicotine source.

Assignees

• Philip Morris Products Sa

Inventors

• Malgat Alexandre
• Waller Judith

Classifications

• A61P25/34

  Tobacco-abuse · CPC title

• A61M2205/36

  related to heating or cooling · CPC title

• A61M11/04

  operated by the vapour pressure of the liquid to be sprayed or atomised {(air-humidification, e.g. "room humidifiers" F24F6/00)} · CPC title

• A61M15/0003

  with means for dispensing more than one drug · CPC title

• A61M11/00 Primary

  Sprayers or atomisers specially adapted for therapeutic purposes (in general B05B; {aerosol containers B65D83/14}) · CPC title