Fabric-base biochemical detecting device and the fabricating method thereof

Patent metadata

Field	Value
Publication number	US-2016109435-A1
Application number	US-201514692332-A
Country	US
Kind code	A1
Filing date	Apr 21, 2015
Priority date	Oct 16, 2014
Publication date	Apr 21, 2016
Grant date	—

Abstract

The present invention provides a fabric-base biochemical detecting device and the fabricating method thereof. The device comprises a fabric-base material, a detecting material, and glue. The fabricating method comprises the following steps of: (S 1 ) preparing a fabric-base material, and the basic material is a hydrophobic fabric-base material; (S 2 ) applying a plasma to treat part of the hydrophobic fabric-base material for forming a hydrophilic region on the fabric-base material; (S 3 ) preparing a detecting material to be disposed on the hydrophilic region of the fabric-base material; and (S 4 ) preparing glue for covering the detecting material. The present invention can extend the duration of the detecting material by covering the glue with the detecting material, and have the advantages of simplified manufacture procedure, low cost, and availability of multiple biochemical examinations.

First claim

What is claimed is:

1 . A fabric-base biochemical detecting device for a biochemical detection of an analyte, comprising:
a fabric-base material, comprising a hydrophilic region and a hydrophobic region; a detecting material, disposed on the hydrophilic region; and a glue, covering the detecting material; wherein when the analyte is contacted with the glue, the analyte penetrates through the glue and contacts with the detecting material, and the biochemical detection is completed by changing the color of the detecting material.

2 . The biochemical detecting device of claim 1 , wherein the fabric-base material is a hydrophobic fabric-base material, the hydrophilic region is formed by utilizing O 2 plasma, argon plasma or air plasma to process the hydrophobic fabric-base material, and the hydrophobic region is formed from the part of the hydrophobic fabric-base material without being processed by utilizing O 2 plasma, argon plasma or air plasma.

3 . The biochemical detecting device of claim 1 , wherein the hydrophilic region and the hydrophobic region of the fabric-base material are formed by interweaving a hydrophilic fabric-base material and the hydrophobic fabric-base material

4 . The biochemical detecting device of claim 1 , wherein the fabric-base material is the hydrophilic fabric-base material, the hydrophobic region is formed by utilizing wax or water-proof ink to process the hydrophilic fabric-base material, and the hydrophilic region is formed from the part of the hydrophilic fabric-base material without being processed by utilizing wax or water-proof ink.

5 . The biochemical detecting device of claim 1 , wherein the glue is formed by mixing 10% to 15% PVA particles and water.

6 . The biochemical detecting device of claim 1 , wherein if the analyte is blood, the detecting material comprises a glucose detection reagent or a blood urea nitrogen detection reagent; if the analyte is saliva, the detecting material comprises a pH detection reagent, a glucose detection reagent, an uric acid detection reagent or a nitrite detection reagent; if the analyte is urine, the detecting material comprises a pH detection reagent, a glucose detection reagent, an urinary protein detection reagent, a nitrite detection reagent, a bilirubin detection reagent, a urobilinogen detection reagent or a ketone body detection reagent; if the analyte is tear, the detecting material comprises a glucose detection reagent; if the analyte is vaginal discharge, the detecting material comprises a pH detection reagent, a glycogen detection reagent or a lactic acid detection reagent; if the analyte is tissue fluid of the skin wound, the detecting material comprises a type XVII collagen with the structure of the NC16A, an IgG antibody with the HRP, a 3, 3′, 5, 5′-tetramethylbenzidine and a dihydrogen dioxide.

7 . A manufacturing method for a fabric-base biochemical detecting device, comprising the following steps of:
(S 1 ) preparing a fabric-base material, wherein the fabric-base material is a hydrophobic fabric-base material; (S 2 ) utilizing a plasma to process part of the hydrophobic fabric-base material to form a hydrophilic region and a hydrophobic region; (S 3 ) preparing a detecting material disposed on the hydrophilic region of the fabric-base material; and (S 4 ) preparing a glue for covering the detecting material; wherein when the analyte is contacted with the glue, the analyte penetrates through the glue and contacts with the detecting material, and the biochemical detection is completed by changing the color of the detecting material.

8 . The manufacturing method of claim 7 , wherein the plasma comprises O 2 plasma, argon plasma or air plasma and so on.

9 . The manufacturing method of claim 7 , wherein the glue is formed by mixing 10% to 15% PVA particles and water.

10 . The manufacturing method of claim 7 , wherein if the analyte is blood, the detecting material comprises a glucose detection reagent or a blood urea nitrogen detection reagent; if the analyte is saliva, the detecting material comprises a pH detection reagent, a glucose detection reagent, an uric acid detection reagent or a nitrite detection reagent; if the analyte is urine, the detecting material comprises a pH detection reagent, a glucose detection reagent, an urinary protein detection reagent, a nitrite detection reagent, a bilirubin detection reagent, a urobilinogen detection reagent or a ketone body detection reagent; if the analyte is tear, the detecting material comprises a glucose detection reagent; if the analyte is vaginal discharge, the detecting material comprises a pH detection reagent, a glycogen detection reagent or a lactic acid detection reagent; if the analyte is tissue fluid of the skin wound, the detecting material comprises a type XVII collagen with the structure of the NC16A, the IgG antibody with the HRP, the 3, 3′, 5, 5′-tetramethylbenzidine and a dihydrogen dioxide.

11 . A manufacturing method for a fabric-base biochemical detecting device, comprising the following steps of:
(K 1 ) preparing a hydrophobic fabric-base material and a hydrophilic fabric-base material; (K 2 ) interweaving the hydrophobic fabric-base material and the hydrophilic fabric-base material to form the fabric-base material with the hydrophilic region; (K 3 ) preparing a detecting material disposed on the hydrophilic region of the fabric-base material; and (K 4 ) preparing a glue for covering the detecting material; wherein when the analyte is contacted with the glue, the analyte penetrates through the glue and contacts with the detecting material, and the biochemical detection is completed by changing the color of the detecting material.

12 . The manufacturing method of claim 11 , wherein the glue is formed by mixing 10% to 15% PVA particles and water.

13 . The manufacturing method of claim 11 , wherein if the analyte is blood, the detecting material comprises a glucose detection reagent or a blood urea nitrogen detection reagent; if the analyte is saliva, the detecting material comprises a pH detection reagent, a glucose detection reagent, an uric acid detection reagent or a nitrite detection reagent; if the analyte is urine, the detecting material comprises a pH detection reagent, a glucose detection reagent, an urinary protein detection reagent, a nitrite detection reagent, a bilirubin detection reagent, a urobilinogen detection reagent or a ketone body detection reagent; if the analyte is tear, the detecting material comprises a glucose detection reagent; if the analyte is vaginal discharge, the detecting material comprises a pH detection reagent, a glycogen detection reagent or a lactic acid detection reagent; if the analyte is tissue fluid of the skin wound, the detecting material comprises a type XVII collagen with the structure of the NC16A, the IgG antibody with the HRP, the 3, 3′, 5, 5′-tetramethylbenzidine and a dihydrogen dioxide.

14 . A manufacturing method for a fabric-base biochemical detecting device, comprising the following steps of:
(G 1 ) preparing a fabric-base material, wherein the fabric-base material is a hydrophilic fabric-base material; (G 2 ) utilizing a hydrophobic material to process part of the hydrophilic fabric-base material to form a hydrophobic region and a hydrophilic region on the fabric-base material; (G 3 ) preparing a detecting material disposed on the hydrophilic region of the fabric-base material; and (G 4 ) preparing a glue for covering the detecting material;
wherein when the analyte is contacted with the glue, the analyte penetrates through the glue and contacts with the detecting material, and the biochemi

Assignees

• Nat Univ Tsing Hua

Inventors

• Yang Chung-Yao
• Cheng Chao-Min
• Lin Szu-Ting
• Yeh Jer-Liang

Classifications

• G01N21/78 Primary

  producing a change of colour · CPC title

• D06M10/025

  Corona discharge or low temperature plasma · CPC title

• G01N2021/7796

  Special mountings, packaging of indicators · CPC title

• G01N33/525 Primary

  Multi-layer analytical elements · CPC title

• G01N33/521

  Single-layer analytical elements · CPC title