Hydrogels comprising cell adhesive peptides and methods of use thereof
US-2024376438-A1 · Nov 14, 2024 · US
US2016103121A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016103121-A1 |
| Application number | US-201414763481-A |
| Country | US |
| Kind code | A1 |
| Filing date | Feb 13, 2014 |
| Priority date | Feb 13, 2013 |
| Publication date | Apr 14, 2016 |
| Grant date | — |
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An object of the present invention is to elucidate a molecular mechanism of ligand-independent activation of EphA2 in cancer cells, make EphA2 a more useful target in the treatment of cancer, and provide a cancer testing method and the like using the mechanism. The present invention provides, for example, a cancer testing method including a step of measuring an amount of an EphA2 protein fragment having a molecular weight of from 30 kDa to 80 kDa in a sample derived from a subject.
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1 . A method of testing cancer, comprising a step of measuring an amount of a fragment of EphA2 protein having a molecular weight of from 30 kDa to 80 kDa in a sample derived from a subject. 2 . The method according to claim 1 , wherein the fragment of EphA2 protein is a fragment comprising an N terminal of EphA2 protein. 3 . The method according to claim 1 , wherein the fragment of EphA2 protein is at least one of the following peptides (i) to (iii)…
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