Genetically modified bacillus subtilis strain and use as a live delivery and production system
US-2024390433-A1 · Nov 28, 2024 · US
US2016100618A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016100618-A1 |
| Application number | US-201514973166-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 17, 2015 |
| Priority date | Oct 21, 2005 |
| Publication date | Apr 14, 2016 |
| Grant date | — |
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The present invention relates to methods for feeding and to compositions to be administered to infants delivered via caesarian section and in particular to the use of a) at least two different microorganisms; or b) at least one microorganism and at least one indigestible oligosaccharide; or c)at least two different Bifidobacteria species, subspecies or strains for the manufacture of a composition for enteral administration to an infant delivered via caesarean section. Thereby it is possible to stimulate the healthy development of the intestinal flora of said infants.
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1 . A method for feeding an infant delivered via caesarean section, wherein said method comprises: (i) identifying an infant delivered via caesarean section; and (ii) enterally administering to the infant a composition comprising: (a) a Bifidobacterium consisting of Bifidobacterium breve; and (b) at least one indigestible galacto-oligosaccharide. 2 . The method of claim 1 , wherein the composition further comprises an indigestible oligosaccharide selected from the group consisting of indigestible dextrins, xylooligosaccharides, arabinooligosaccharides, glucooligosaccharides, mannooligo-saccharides, isomalto-oligosaccharide and fructopolysaccharides. 3 . The method of claim 1 , wherein the composition comprises between 5 and 25 energy % protein, between 25 and 60 energy % fat and between 30 and 70 energy % carbohydrate. 4 . The method of claim 1 , wherein the composition is administered to an infant receiving human breast milk. 5 . The method of claim 1 , wherein the composition is administered to the infant within one week after birth. 6 . The method of claim 1 , wherein the composition is admixed with a nutritionally or pharmaceutically acceptable liquid prior to administering the composition to the infant. 7 . The method of claim 1 , wherein the composition stimulates the intestinal flora of the infant. 8 . The method of claim 7 , wherein the composition is administered to the infant within 100 hours after birth.
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