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US-2024316020-A1 · Sep 26, 2024 · US
Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant
US2016015644A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016015644-A1 |
| Application number | US-201414760883-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jan 14, 2014 |
| Priority date | Jan 15, 2013 |
| Publication date | Jan 21, 2016 |
| Grant date | — |
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Abstract
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Disclosed herein are novel compositions and methods for controlling the release of bile acid sequestrant to the stomach in order to treat or prevent upper GI tract disorders or disorders of the throat. The methods generally include administering to a patient in need thereof a therapeutically effective amount of a pharmaceutical composition comprising at least one bile acid sequestrant dispersed in a polymeric matrix. The bite acid sequestrant composition may be administered alone or in combination with at least one proton pump inhibitor, and optionally one or more agents chosen from antacids, histamine H 2 -receptor antagonists, γ-aminobutyric acid-β (GABA-B) agonists, prodrugs of GABA-B agonists, acid pump antagonists, protease inhibitors and GC-C agonists.
First claim
Opening claim text (preview).
We claim: 1 . A gastro-retentive, oral dosage form for sustained release of a bile acid sequestrant to the stomach for the treatment of a disease of the upper gastrointestinal tract or the throat, wherein said dosage form comprises a bile acid sequestrant dispersed in a polymeric matrix, wherein the polymeric matrix comprises one or more hydrophilic polymers such dial, upon imbibition of gastric fluid, said dosage form swells to a size sufficient to promote gastric retention for…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US2016015644A1 cover?
- Disclosed herein are novel compositions and methods for controlling the release of bile acid sequestrant to the stomach in order to treat or prevent upper GI tract disorders or disorders of the throat. The methods generally include administering to a patient in need thereof a therapeutically effective amount of a pharmaceutical composition comprising at least one bile acid sequestrant dispersed…
- Who is the assignee on this patent?
- Ironwood Pharmaceuticals Inc
- What technology area does this patent fall under?
- Primary CPC classification A61K9/2054. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Thu Jan 21 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).