Baroreceptor mapping system

Patent metadata

Field	Value
Publication number	US-2015366465-A1
Application number	US-201514743954-A
Country	US
Kind code	A1
Filing date	Jun 18, 2015
Priority date	Jun 19, 2014
Publication date	Dec 24, 2015
Grant date	—

Abstract

A system for mapping and marking baroreceptors of a patient. The system includes a mapping device, a marker, and a stimulator. The mapping device includes a plurality of electrodes to be situated on the patient. The marker is to be attached to the patient and mark a location of at least one of the plurality of electrodes based on an analysis of patient physiological responses to stimulation of the plurality of electrodes. The stimulator is to divide the plurality of electrodes into a first electrode zone and a second electrode zone and stimulate electrodes in the first electrode zone and the second electrode zone to obtain first patient physiological responses, where one of the first electrode zone and the second electrode zone is selected based on the first patient physiological responses.

First claim

We claim:

1 . A system for mapping and marking baroreceptors of a patient, comprising:
a mapping device that includes a plurality of electrodes to be situated on the patient; and a stimulator to divide the plurality of electrodes into a first electrode zone and a second electrode zone and to stimulate electrodes in the first electrode zone and in the second electrode zone to obtain patient physiological responses, wherein one of the first electrode zone and the second electrode zone is selected based on the patient physiological responses.

2 . The system of claim 1 , wherein the stimulator is to divide the selected one of the first electrode zone and the second electrode zone into a third electrode zone and a fourth electrode zone and to stimulate electrodes in the third electrode zone and the fourth electrode zone to obtain the patient physiological responses.

3 . The system of claim 2 , wherein one of the third electrode zone and the fourth electrode zone is selected as providing more effective patient physiological responses.

4 . The system of claim 1 , wherein the stimulator is to select at least one cathode electrode in the first electrode zone and at least one anode electrode in the second electrode zone and provide electrical stimulation to the selected electrodes to obtain first patient physiological responses.

5 . The system of claim 4 , wherein the stimulator switches to select the at least one cathode electrode in the second electrode zone and the at least one anode electrode in the first electrode zone and provide electrical stimulation to the selected electrodes to obtain second patient physiological responses.

6 . The system of claim 5 , wherein the stimulator compares the first patient physiological responses and the second patient physiological responses to select the one of the first electrode zone and the second electrode zone.

7 . The system of claim 1 , comprising a marker to be attached to the patient to mark a location of at least one of the plurality of electrodes based on the patient physiological responses.

8 . The system of claim 1 , wherein the patient physiological responses are changes in one of patient blood pressure, patient heart rate, and patient tissue impedance.

9 . The system of claim 1 , comprising a sensor to sense the patient physiological responses and provide signals that indicate the patient physiological responses.

10 . The system of claim 9 , wherein the stimulator receives the signals and analyzes the signals to determine the patient physiological responses and the one of the first electrode zone and the second electrode zone that is selected based on the patient physiological responses.

11 . A method of mapping and marking baroreceptors, comprising:
maintaining a mapping device on a patient, the mapping device including a plurality of electrodes on the patient; dividing the plurality of electrodes, via a stimulator, into a first electrode zone and a second electrode zone; stimulating electrodes in the first electrode zone and the second electrode zone with the stimulator to obtain patient physiological responses; and selecting one of the first electrode zone and the second electrode zone based on the patient physiological responses.

12 . The method of claim 11 , comprising:
dividing the selected one of the first electrode zone and the second electrode zone, via the stimulator, into a third electrode zone and a fourth electrode zone; and stimulating electrodes in the third electrode zone and the fourth electrode zone with the stimulator to obtain more patient physiological responses.

13 . The method of claim 12 , comprising:
selecting one of the third electrode zone and the fourth electrode zone based on the patient physiological responses including the more patient physiological response.

14 . The method of claim 11 , comprising:
attaching a marker to the patient to mark a location of at least one of the plurality of electrodes based on an analysis of the patient physiological responses.

15 . The method of claim 11 , wherein stimulating electrodes in the first electrode zone and the second electrode zone comprises:
selecting at least one cathode electrode in the first electrode zone; selecting at least one anode electrode in the second electrode zone; and stimulating, via the stimulator, the selected electrodes to obtain the patient physiological responses.

16 . The method of claim 15 , wherein stimulating electrodes in the first electrode zone and the second electrode zone comprises:
selecting at least one cathode electrode in the second electrode zone; selecting at least one anode electrode in the first electrode zone; and stimulating, via the stimulator, the selected electrodes to obtain the patient physiological responses.

17 . The method of claim 11 , comprising:
sensing the patient physiological responses with a sensor; providing signals that indicate the patient physiological responses; receiving the signals at the stimulator; and analyzing the signals with the stimulator to determine the one of the first electrode zone and the second electrode zone that is selected based on the patient physiological responses.

18 . One or more non-transitory computer-readable storage media having computer-executable instructions embodied thereon that, when executed by a processor, cause the processor to provide a method comprising:
dividing a plurality of electrodes on a mapping device into a first electrode zone and a second electrode zone; selecting at least one cathode electrode in the first electrode zone; selecting at least one anode electrode in the second electrode zone; stimulating the at least one cathode electrode in the first electrode zone and the at least one anode electrode in the second electrode zone to obtain first patient physiological responses; selecting at least one cathode electrode in the second electrode zone; selecting at least one anode electrode in the first electrode zone; stimulating the at least one cathode electrode in the second electrode zone and the at least one anode electrode in the first electrode zone to obtain second patient physiological responses; and comparing the first patient physiological responses and the second patient physiological responses to select one of the first electrode zone and the second electrode zone.

19 . The media of claim 18 , wherein the method comprises:
dividing the selected one of the first electrode zone and the second electrode zone into a third electrode zone and a fourth electrode zone; selecting at least one cathode electrode in the third electrode zone; selecting at least one anode electrode in the fourth electrode zone; stimulating the at least one cathode electrode in the third electrode zone and the at least one anode electrode in the fourth electrode zone to obtain third patient physiological responses; selecting at least one cathode electrode in the fourth electrode zone; selecting at least one anode electrode in the third electrode zone; stimulating the at least one cathode electrode in the fourth electrode zone and the at least one anode electrode in the third electrode zone to obtain fourth patient physiological responses; and comparing the third patient physiological responses and the fourth patient physiological responses to select one of the third electrode zone and the fourth electrode zone.

20 . The media of claim 18 , wherein the method comprises:
receiving signals from a sensor; and analyzing the sig

Assignees

• Cardiac Pacemakers Inc

Inventors

• De Kock Andrew L
• Mokelke Eric A
• Soltis Brian
• Giwoyna Doug E
• Blood James E

Classifications

• A61B5/024

  Measuring pulse rate or heart rate · CPC title

• A61N1/0476

  Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities) · CPC title

• A61B5/053

  Measuring electrical impedance or conductance of a portion of the body · CPC title

• A61B5/0215

  by means inserted into the body · CPC title

• A61B5/0531

  Measuring skin impedance · CPC title