Cyclodextrin Functionalized Nanoparticles for Quenching Bacterial Communications

US2015315298A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2015315298-A1
Application numberUS-201514677328-A
CountryUS
Kind codeA1
Filing dateApr 2, 2015
Priority dateApr 2, 2014
Publication dateNov 5, 2015
Grant date

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  1. Title

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  5. First independent claim

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Abstract

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A method is generally provided for attaching a polymer chain onto a surface of a nanoparticle, where the polymer chain comprises a cyclic arrangement of saccharides. The resulting grafted nanoparticle is also generally provided, along with its methods of use by exposing to a bacteria colony.

First claim

Opening claim text (preview).

What is claimed: 1 . A method, comprising: attaching a polymer chain onto a surface of a nanoparticle, wherein the polymer chain comprises a cyclic arrangement of saccharides. 2 . The method as in claim 1 , wherein the cyclic arrangement of saccharides is a cyclodextrin. 3 . The method as in claim 1 , wherein the cyclic arrangement of saccharides is a cyclodextrin derivative. 4 . The method as in claim 1 , wherein the cyclic arrangement of saccharides comprises α-cyclodextrin. 5 . The method as in claim 1 , wherein the cyclic arrangement of saccharides comprises β-cyclodextrin. 6 . The method as in claim 1 , wherein the cyclic arrangement of saccharides comprises γ-cyclodextrin. 7 . The method as in claim 1 , wherein the molecular weight of the surface attached polymer chain is from about 500 to about 200,000 g/mol. 8 . The method as in claim 1 , wherein the polymer chain is attached to the surface of the nanoparticle via an anchoring compound. 9 . The method as in claim 1 , wherein a second polymeric chain is also attached to the surface of the nanoparticle to form a bi-modal nanoparticle. 10 . A grafted nanoparticle, comprising: a nanoparticle defining a surface; and a polymer chain covalently bonded to the surface of the nanoparticle, wherein the polymer chain comprises a cyclic arrangement of saccharides. 11 . The grafted nanoparticle as in claim 10 , wherein the polymer chain is covalently bonded to the surface of the nanoparticle via an anchoring compound. 12 . The grafted nanoparticle as in claim 10 , wherein the cyclic arrangement of saccharides is a cyclodextrin. 13 . The grafted nanoparticle as in claim 10 , wherein the cyclic arrangement of saccharides is a cyclodextrin derivative. 14 . The grafted nanoparticle as in claim 10 , wherein the cyclic arrangement of saccharides comprises α-cyclodextrin. 15 . The grafted nanoparticle as claim 10 , wherein the cyclic arrangement of saccharides comprises β-cyclodextrin. 16 . The grafted nanoparticle as in claim 10 , wherein the cyclic arrangement of saccharides comprises γ-cyclodextrin. 17 . The grafted nanoparticle as in claim 10 , wherein the molecular weight of the surface attached polymer chain is from about 500 to about 200,000 g/mol. 18 . The grafted nanoparticle as in claim 10 , wherein the polymer chain is attached to the surface of the nanoparticle via an anchoring compound. 19 . The grafted nanoparticle as in claim 10 , wherein a second polymeric chain is also attached to the surface of the nanoparticle to form a bi-modal nanoparticle. 20 . A method of capturing signaling molecules, comprising: exposing a bacteria colony to the grafted nanoparticle of claim 10 .

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Classifications

  • Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof · CPC title

  • obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin · CPC title

  • Cyclodextrin; Derivatives thereof · CPC title

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What does patent US2015315298A1 cover?
A method is generally provided for attaching a polymer chain onto a surface of a nanoparticle, where the polymer chain comprises a cyclic arrangement of saccharides. The resulting grafted nanoparticle is also generally provided, along with its methods of use by exposing to a bacteria colony.
Who is the assignee on this patent?
Univ South Carolina
What technology area does this patent fall under?
Primary CPC classification C08B37/0012. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Thu Nov 05 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).